Feskens E J, Bowles C H, Kromhout D
Department of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
Am J Clin Nutr. 1991 Jul;54(1):136-40. doi: 10.1093/ajcn/54.1.136.
The association between the intake of carbohydrates, body mass index (BMI), and the 4-y incidence of impaired glucose tolerance and diabetes mellitus (glucose intolerance) was investigated in elderly men and women aged 64-87 y. In 1971 the baseline population consisted of 175 normoglycemic subjects. During the follow-up period (1972-1975) an oral glucose-tolerance test (OGTT) was carried out annually. In univariate analyses, baseline BMI and the habitual intake of carbohydrates and pastries, as determined from a cross-check dietary history, were positively associated with the incidence of glucose intolerance. The habitual intake of legumes was inversely related to the incidence of glucose intolerance. These results could not be explained by potential confounding factors such as age, gender, alcohol use, energy intake, prescribed diet, medication use, and comorbidity. These results suggest that energy balance and the use of carbohydrate-rich foods are related to the development of glucose intolerance in an elderly population.
对64至87岁的老年男性和女性进行了研究，以探讨碳水化合物摄入量、体重指数（BMI）与糖耐量受损和糖尿病（葡萄糖不耐受）4年发病率之间的关联。1971年，基线人群包括175名血糖正常的受试者。在随访期间（1972 - 1975年），每年进行一次口服葡萄糖耐量试验（OGTT）。在单变量分析中，根据交叉核对饮食史确定的基线BMI、碳水化合物和糕点的习惯性摄入量与葡萄糖不耐受的发病率呈正相关。豆类的习惯性摄入量与葡萄糖不耐受的发病率呈负相关。这些结果无法用年龄、性别、饮酒、能量摄入、规定饮食、药物使用和合并症等潜在混杂因素来解释。这些结果表明，能量平衡和富含碳水化合物食物的摄入与老年人群葡萄糖不耐受的发生有关。
