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An enantioselective total synthesis of (+)-peloruside A.

作者信息

McGowan Meredeth A, Stevenson Christian P, Schiffler Matthew A, Jacobsen Eric N

机构信息

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford St., Cambridge, MA 02138, USA.

出版信息

Angew Chem Int Ed Engl. 2010 Aug 16;49(35):6147-50. doi: 10.1002/anie.201002177.

Abstract
摘要

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本文引用的文献

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Regio- and Enantioselective Cyclization of Epoxy Alcohols Catalyzed by a [Co(salen)] Complex.
Angew Chem Int Ed Engl. 1999 Jul 12;38(13-14):2012-2014. doi: 10.1002/(SICI)1521-3773(19990712)38:13/14<2012::AID-ANIE2012>3.0.CO;2-H.
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An aldol-based synthesis of (+)-peloruside a, a potent microtubule stabilizing agent.
J Am Chem Soc. 2009 Mar 25;131(11):3840-1. doi: 10.1021/ja900020a.
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Enantioselective total synthesis of peloruside A: a potent microtubule stabilizer.
Org Lett. 2008 Mar 6;10(5):1001-4. doi: 10.1021/ol703091b. Epub 2008 Feb 5.
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Total synthesis of (+)-peloruside A.
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Total synthesis and absolute configuration of the novel microtubule-stabilizing agent peloruside A.
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The practical synthesis of a novel and highly potent analogue of bryostatin.
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Highly enantioselective inverse-electron-demand hetero-diels-alder reactions of alpha,beta-unsaturated aldehydes.
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