伯氏疏螺旋体基因座连锁的地理差异。
Geographic differences in genetic locus linkages for Borrelia burgdorferi.
机构信息
University of California, Irvine, California 92697-4028, USA.
出版信息
Emerg Infect Dis. 2010 Jul;16(7):1147-50. doi: 10.3201/eid1607.091452.
Abstract
Borrelia burdorferi genotype in the northeastern United States is associated with Lyme borreliosis severity. Analysis of DNA sequences of the outer surface protein C gene and rrs-rrlA intergenic spacer from extracts of Ixodes spp. ticks in 3 US regions showed linkage disequilibrium between the 2 loci within a region but not consistently between regions.
摘要
美国东北部的伯氏疏螺旋体基因型与莱姆病的严重程度有关。对来自美国 3 个地区的硬蜱属 Ixodes spp. 提取物的外表面蛋白 C 基因和 rrs-rrlA 基因间隔区的 DNA 序列进行分析表明，在一个区域内，2 个基因座之间存在连锁不平衡，但在不同区域之间并不一致。
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