L 型牛朊病毒在周围神经组织中的积累。
Accumulation of L-type bovine prions in peripheral nerve tissues.
机构信息
National Institute of Animal Health, Tsukuba, Ibaraki 305-0856, Japan.
出版信息
Emerg Infect Dis. 2010 Jul;16(7):1151-4. doi: 10.3201/eid1607.091882.
Abstract
We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues.
摘要
我们最近报道了 L 型非典型牛海绵状脑病（BSE）的种内传播。为了阐明 L 型 BSE 的外周发病机制，我们研究了从实验性感染牛获得的神经和淋巴组织中的朊病毒分布。与经典 BSE 朊病毒一样，L 型 BSE 朊病毒在中枢和周围神经组织中积累。
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