Okada Hiroyuki, Iwamaru Yoshifumi, Imamura Morikazu, Miyazawa Kohtaro, Matsuura Yuichi, Masujin Kentaro, Murayama Yuichi, Yokoyama Takashi
Emerg Infect Dis. 2017 Feb;23(2):284-287. doi: 10.3201/eid2302.161416.
To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.
为确定L型牛海绵状脑病(BSE)朊病毒的经口传播性,我们用该病原体的脑匀浆对16头犊牛进行了经口接种。只有1头接受高剂量接种的动物出现症状,并在88个月时死亡。这些结果表明,L型BSE病原体在牛群中经口传播的风险较低。