Dept. of Psychiatry, Naval Medical Center, Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, USA.
Psychosomatics. 2010 Jul-Aug;51(4):340-4. doi: 10.1176/appi.psy.51.4.340.
For decades, anabolic-androgenic steroids have been abused to enhance muscle growth. The harm inflicted by these compounds is well documented.
The authors investigated and report on a case in which a male patient self-prescribed some newer dietary supplements, about which less is known.
The authors report on a case of hepatitis and aggressive personality changes in a 31-year-old man taking purported prohormone agent SUS500 and other, newer supplements.
Diagnosis was based on history, mental status exam, and laboratory findings. With discontinuation of all supplements and supportive care, the patient's personality changes resolved, and normal liver function returned.
The authors conclude that newer anabolic supplements may cause some of the same side effects as traditional steroid hormones.
几十年来，合成代谢雄激素类固醇一直被滥用以促进肌肉生长。这些化合物造成的危害已有充分记录。
作者调查并报告了一个男性患者自行服用一些较新的膳食补充剂的案例，这些补充剂的相关信息较少。
作者报告了一个 31 岁男性服用所谓的促激素 SUS500 和其他较新补充剂后出现肝炎和攻击性人格改变的病例。
诊断基于病史、精神状态检查和实验室发现。停用所有补充剂并给予支持性治疗后，患者的人格改变得到解决，肝功能恢复正常。
作者得出结论，较新的合成代谢补充剂可能会引起与传统类固醇激素相同的一些副作用。
