Ha J Y, Shishkov M, Colice M, Oh W Y, Yoo H, Liu L, Tearney G J, Bouma B E
Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital 50 Blossom Street, BAR-7, Boston Massachusetts 02114, USA.
Opt Express. 2010 May 24;18(11):11418-27. doi: 10.1364/OE.18.011418.
A novel heterodyne Doppler interferometer method for compensating motion artifacts caused by cardiac motion in intracoronary optical frequency domain imaging (OFDI) is demonstrated. To track the relative motion of a catheter with regard to the vessel, a motion tracking system is incorporated with a standard OFDI system by using wavelength division multiplexing (WDM) techniques. Without affecting the imaging beam, dual WDM monochromatic beams are utilized for tracking the relative radial and longitudinal velocities of a catheter-based fiber probe. Our results demonstrate that tracking instantaneous velocity can be used to compensate for distortion in the images due to motion artifacts, thus leading to accurate reconstruction and volumetric measurements with catheter-based imaging.
本文展示了一种新颖的外差式多普勒干涉仪方法，用于补偿冠状动脉光学频域成像（OFDI）中心脏运动引起的运动伪影。为了跟踪导管相对于血管的相对运动，通过使用波分复用（WDM）技术，将运动跟踪系统与标准OFDI系统相结合。在不影响成像光束的情况下，利用双WDM单色光束来跟踪基于导管的光纤探头的相对径向和纵向速度。我们的结果表明，跟踪瞬时速度可用于补偿由于运动伪影导致的图像失真，从而实现基于导管成像的精确重建和容积测量。
