Rosenberg H, Singer M, Rosenberg M
Science. 1978 Apr 28;200(4340):394-402. doi: 10.1126/science.205944.
A 172-base pair segment of DNA that is repeated several million times in the genome of the African green monkey has been characterized. Sequence analysis revealed that the many repeats of this complex unit are not all identical but represent a set of closely related segments: Sequence divergence occurs at various positions in the segment in a nonrandom manner. The uncloned segment obtained from monkey DNA is compared with a cloned segment of the same DNA which was recombined into the genome of simian virus 40 during permissive infection.
一段172个碱基对的DNA片段在非洲绿猴基因组中重复了数百万次，其特征已被确定。序列分析表明，这个复杂单元的许多重复序列并非完全相同，而是代表一组密切相关的片段：序列差异以非随机方式出现在该片段的不同位置。将从猴DNA中获得的未克隆片段与在允许感染期间重组到猿猴病毒40基因组中的相同DNA的克隆片段进行比较。
