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对单个猴子染色体上的LINE-1家族序列的分析。

Analysis of LINE-1 family sequences on a single monkey chromosome.

作者信息

Lee T N, Singer M F

出版信息

Nucleic Acids Res. 1986 May 12;14(9):3859-70. doi: 10.1093/nar/14.9.3859.

DOI:10.1093/nar/14.9.3859
PMID:3012483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC339820/
Abstract

The structure of LINE-1 (L1Ca) family members present on African green monkey chromosome CAE-19 is compared with that of the entire set of L1Ca sequences present in the monkey genome. The analysis involved annealing of cloned subsegments of monkey L1 family members to DNA-blots containing restriction endonuclease digests of either total monkey liver DNA or DNA isolated from a monkey/mouse somatic cell hybrid carrying the single monkey chromosome. In addition, L1Ca segments cloned from hybrid cell DNA were characterized by restriction endonuclease mapping and hybridization. The data indicate that, taken as a whole, the set of L1Ca sequences on CAE-19 tends to differ in characteristic ways from the set present in the total monkey genome.

摘要

将非洲绿猴染色体CAE - 19上存在的LINE - 1（L1Ca）家族成员的结构与猴基因组中存在的整套L1Ca序列的结构进行比较。该分析涉及将猴L1家族成员的克隆亚片段与包含总猴肝DNA或从携带单条猴染色体的猴/鼠体细胞杂种中分离的DNA的限制性内切酶消化产物的DNA印迹进行退火。此外，通过限制性内切酶图谱分析和杂交对从杂种细胞DNA中克隆的L1Ca片段进行表征。数据表明，总体而言，CAE - 19上的L1Ca序列集在特征上倾向于与总猴基因组中存在的序列集不同。

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本文引用的文献

1
Interruption of an alpha-satellite array by a short member of the KpnI family of interspersed, highly repeated monkey DNA sequences.散布的高度重复的猴DNA序列的KpnI家族的一个短成员对α-卫星阵列的中断。
Mol Cell Biol. 1983 Jun;3(6):967-73. doi: 10.1128/mcb.3.6.967-973.1983.
2
Looking for relationships between the most repeated dispersed DNA sequences in the mouse: small R elements are found associated consistently with long MIF repeats.寻找小鼠中最常见的分散DNA序列之间的关系：发现小R元件始终与长MIF重复序列相关联。
EMBO J. 1984 Feb;3(2):467-72. doi: 10.1002/j.1460-2075.1984.tb01829.x.
3
A large interspersed repeat found in mouse DNA contains a long open reading frame that evolves as if it encodes a protein.
在小鼠DNA中发现的一个大的散布重复序列包含一个长的开放阅读框，其进化方式就好像它编码一种蛋白质。
Proc Natl Acad Sci U S A. 1984 Apr;81(8):2308-12. doi: 10.1073/pnas.81.8.2308.
4
Intrachromosomal movement of genetically marked Saccharomyces cerevisiae transposons by gene conversion.通过基因转换实现的遗传标记酿酒酵母转座子的染色体内移动。
Mol Cell Biol. 1984 Apr;4(4):703-11. doi: 10.1128/mcb.4.4.703-711.1984.
5
The L1Md long interspersed repeat family in the mouse: almost all examples are truncated at one end.小鼠中的L1Md长散在重复序列家族：几乎所有实例在一端都是截短的。
Nucleic Acids Res. 1983 Dec 20;11(24):8847-59. doi: 10.1093/nar/11.24.8847.
6
Rearranged sequences of a human Kpn I element.人类Kpn I元件的重排序列。
Proc Natl Acad Sci U S A. 1984 Feb;81(4):1012-6. doi: 10.1073/pnas.81.4.1012.
7
Some KpnI family members are associated with the Alu family in the human genome.在人类基因组中，一些KpnI家族成员与Alu家族相关联。
Nucleic Acids Res. 1983 Oct 11;11(19):6837-46. doi: 10.1093/nar/11.19.6837.
8
Organization of the R family and other interspersed repetitive DNA sequences in the mouse genome.小鼠基因组中R家族及其他散布重复DNA序列的组织方式。
J Mol Biol. 1983 Oct 25;170(2):255-70. doi: 10.1016/s0022-2836(83)80147-8.
9
Homology between the KpnI primate and BamH1 (M1F-1) rodent families of long interspersed repeated sequences.灵长类动物KpnI家族与啮齿动物BamH1（M1F-1）家族长散在重复序列之间的同源性。
Nucleic Acids Res. 1983 Aug 25;11(16):5739-45. doi: 10.1093/nar/11.16.5739.
10
Size and structure of the highly repetitive BAM HI element in mice.小鼠中高度重复的BAM HI元件的大小和结构。
Nucleic Acids Res. 1983 Aug 11;11(15):5073-91. doi: 10.1093/nar/11.15.5073.