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一个猴Alu序列由13个碱基对的同向重复序列侧翼包围,并被一个中断的α卫星DNA序列隔开。

A monkey Alu sequence is flanked by 13-base pair direct repeats by an interrupted alpha-satellite DNA sequence.

作者信息

Grimaldi G, Singer M F

出版信息

Proc Natl Acad Sci U S A. 1982 Mar;79(5):1497-500. doi: 10.1073/pnas.79.5.1497.

Abstract

A member of the Alu family, the dominant family of short interspersed repeated DNA sequences in primates, interrupts a cloned repeat unit of African green monkey alpha-satellite DNA. The Alu is immediately flanked by 13-base-pair duplications of the known sequence of the satellite at the site of insertion. These observations support the idea that Ala family members may be moveable elements.

摘要

灵长类动物中短散布重复DNA序列的主要家族——Alu家族的一个成员,打断了非洲绿猴α卫星DNA的一个克隆重复单元。在插入位点,Alu两侧紧邻着卫星已知序列的13个碱基对重复序列。这些观察结果支持了Alu家族成员可能是可移动元件的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5ba/346001/3efd2353486d/pnas00444-0133-a.jpg

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