携带bla(VIM)和bla(KPC)基因的肺炎克雷伯菌的出现。
Emergence of Klebsiella pneumoniae carrying bla(VIM) and bla(KPC) genes.
作者信息
Meletis G, Tzampaz E, Protonotariou E, Sofianou D
机构信息
Department of Clinical Microbiology, Hippokratio General Hospital, Thessaloniki, Greece.
出版信息
Hippokratia. 2010 Apr;14(2):139-40.
Abstract
A Klebsiella pneumoniae clinical isolate resistant to imipenem was recovered from a wound sample. The patient, a 57-year-old man, underwent a surgical resection of small bowel and sigmoid colon and was treated with multiple courses of antimicrobials. PCR analysis revealed that the clinical isolate was carrying simultaneously bla(VIM-1), bla(KPC-2), bla(SHV) and bla(TEM) genes. The concomitant presence of these genes is alarming and poses therapeutic as well as infection control problems.
摘要
从一份伤口样本中分离出一株对亚胺培南耐药的肺炎克雷伯菌临床菌株。该患者为一名57岁男性，接受了小肠和乙状结肠的手术切除，并接受了多疗程的抗菌药物治疗。聚合酶链反应（PCR）分析显示，该临床分离株同时携带bla(VIM - 1)、bla(KPC - 2)、bla(SHV)和bla(TEM)基因。这些基因的同时存在令人担忧，并带来了治疗以及感染控制方面的问题。
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