Qiao-Grider Ying, Hung Li-Fang, Kee Chea-Su, Ramamirtham Ramkumar, Smith Earl L
College of Optometry, University of Houston, Houston, TX 77204-2020, United States.
Vision Res. 2010 Aug 23;50(18):1867-81. doi: 10.1016/j.visres.2010.06.008. Epub 2010 Jun 20.
We analyzed the contribution of individual ocular components to vision-induced ametropias in 210 rhesus monkeys. The primary contribution to refractive-error development came from vitreous chamber depth; a minor contribution from corneal power was also detected. However, there was no systematic relationship between refractive error and anterior chamber depth or between refractive error and any crystalline lens parameter. Our results are in good agreement with previous studies in humans, suggesting that the refractive errors commonly observed in humans are created by vision-dependent mechanisms that are similar to those operating in monkeys. This concordance emphasizes the applicability of rhesus monkeys in refractive-error studies.
我们分析了210只恒河猴中各个眼部组成部分对视觉诱导性屈光不正的影响。屈光不正发展的主要影响因素来自玻璃体腔深度；还检测到角膜屈光力有较小影响。然而，屈光不正与前房深度之间或屈光不正与任何晶状体参数之间均无系统性关联。我们的结果与先前对人类的研究结果高度一致，表明人类中常见的屈光不正由与在猴子中起作用的机制类似的视觉依赖机制造成。这种一致性强调了恒河猴在屈光不正研究中的适用性。
