Centro de Biologia da Reprodução, Federal University of Juiz de Fora, Caixa Postal 328, Zip Code 36001-970 Juiz de Fora, MG, Brazil.
Fitoterapia. 2010 Dec;81(8):982-7. doi: 10.1016/j.fitote.2010.06.014. Epub 2010 Jun 25.
This study was aimed at investigating the anti-osteoporotic effects of the extract of Ginkgo biloba (EGb) in glucocorticoid-induced-osteoporosis. A significant reduction was observed in the percentage of the bone of the osteoporosis group in both the mandible and femur. The EGb group treated with 28 and 56 mg/Kg showed a significant increase in the percentage of trabecular bone (PTB) of the femur. The percentage of the alveolar bone of the mandible (PAB) had a significant increase with all doses of EGb. The treatment with EGb significantly reversed the loss of the PAB of the mandible and of the PTB of the femur.
本研究旨在探讨银杏叶提取物（EGb）对糖皮质激素诱导性骨质疏松的抗骨质疏松作用。在颌骨和股骨中，骨质疏松组的骨百分比显著降低。用 28 和 56mg/Kg 的 EGb 治疗的组，股骨的小梁骨（PTB）百分比显著增加。下颌骨的牙槽骨百分比（PAB）在用 EGb 的所有剂量时都有显著增加。EGb 的治疗显著逆转了下颌骨的 PAB 和股骨的 PTB 的丢失。
