Industrial Biotechnology Group, Reliance Life Sciences Pvt. Ltd, Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701, India.
N Biotechnol. 2011 Jan 31;28(1):19-23. doi: 10.1016/j.nbt.2010.06.006. Epub 2010 Jun 25.
The present report describes production of 1,3-propanediol by Klebsiella pneumoniae ATCC 15380 from crude glycerol from jatropha biodiesel process. Optimization resulted in a yield of up to 56g/L of 1,3-propanediol. A conversion rate of 0.85mol 1,3-propanediol/mol of glycerol has been obtained. Downstream processing to isolate 1,3-propanediol from the fermentation broth resulted in 99.7% pure product with a recovery of 34%. The pure 1,3-propanediol was polymerized with terephthalic acid successfully to yield polytrimethylene terephthalate.
本报告描述了从麻疯树生物柴油工艺中的粗甘油中利用肺炎克雷伯氏菌（ATCC 15380）生产 1,3-丙二醇的情况。优化后，1,3-丙二醇的产量高达 56g/L。已获得 0.85mol 1,3-丙二醇/甘油的转化率。从发酵液中分离 1,3-丙二醇的下游处理导致 99.7%纯度的产品回收率为 34%。纯 1,3-丙二醇与对苯二甲酸成功聚合生成聚对苯二甲酸丙二醇酯。
