Lange M, Petermann F
Zentrum für Klinische Psychologie und Rehabilitation der Universität Bremen, Grazer Str. 6, 28359, Bremen, Deutschland.
Schmerz. 2010 Aug;24(4):326-33. doi: 10.1007/s00482-010-0937-8.
Fibromyalgia poses a challenge for therapy. Mainly comorbid depression has a negative impact on symptoms and impairment in patients with fibromyalgia. This paper gives a systematic overview of how depressiveness affects physical and psychological impairment, coping with disease and rehabilitation outcome among patients with fibromyalgia. The databases PubMed, Embase and PsychINFO were searched for studies published up to April 2010.
Fibromyalgia patients with depressive symptoms show more sleep disturbances, sexual dysfunction, loss of physical function level and lower quality of life. Patients with fibromyalgia and comorbid depression showed poorer outcomes of multimodal rehabilitation than patients with fibromyalgia without depression. Therefore the assessment of depression should be included in the routine diagnostics of fibromyalgia. Furthermore, patients with fibromyalgia and comorbid depression should be motivated to seek therapy and get better support in coping with depression.
纤维肌痛对治疗构成挑战。主要是共病的抑郁症会对纤维肌痛患者的症状和功能损害产生负面影响。本文系统综述了抑郁如何影响纤维肌痛患者的身体和心理损害、应对疾病的能力以及康复结果。检索了PubMed、Embase和PsychINFO数据库，查找截至2010年4月发表的研究。
有抑郁症状的纤维肌痛患者表现出更多的睡眠障碍、性功能障碍、身体功能水平下降和生活质量降低。与无抑郁症的纤维肌痛患者相比，伴有抑郁症的纤维肌痛患者多模式康复的效果更差。因此，抑郁症评估应纳入纤维肌痛的常规诊断中。此外，应鼓励伴有抑郁症的纤维肌痛患者寻求治疗，并在应对抑郁症方面获得更好的支持。
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