Varallo Giorgia, Piterà Paolo, Fontana Jacopo Maria, Gobbi Michele, Arreghini Marco, Giusti Emanuele Maria, Franceschini Christian, Plazzi Giuseppe, Castelnuovo Gianluca, Capodaglio Paolo
Department of Medicine and Surgery, University of Parma, 43121 Parma, Italy.
Orthopedic Rehabilitation Unit and Research Laboratory in Biomechanics, Rehabilitation and Ergonomics, Istituto Auxologico Italiano, IRCCS, San Giuseppe Hospital, 28824 Piancavallo, Italy.
J Clin Med. 2022 Jul 26;11(15):4324. doi: 10.3390/jcm11154324.
Pain severity, depression, and sleep disturbances are key targets for FM rehabilitation. Recent evidence suggests that whole-body cryostimulation (WBC) might be an effective add-on treatment in the management of FM. The purpose of this study was to evaluate the effects of an add-on WBC intervention to a multidisciplinary rehabilitation program on pain intensity, depressive symptoms, disease impact, sleep quality, and performance-based physical functioning in a sample of FM patients with obesity. We performed a randomized controlled trial with 43 patients with FM and obesity undergoing a multidisciplinary rehabilitation program with and without the addition of ten 2-min WBC sessions at -110 °C over two weeks. According to our results, the implementation of ten sessions of WBC over two weeks produced additional benefits. Indeed, both groups reported positive changes after the rehabilitation; however, the group that underwent WBC intervention had greater improvements in the severity of pain, depressive symptoms, disease impact, and quality of sleep. On the contrary, with respect to performance-based physical functioning, we found no significant between-group differences. Our findings suggest that WBC could be a promising add-on treatment to improve key aspects of FM, such as pain, depressive symptoms, disease impact and poor sleep quality.
疼痛严重程度、抑郁和睡眠障碍是纤维肌痛康复的关键目标。最近的证据表明，全身冷刺激（WBC）可能是纤维肌痛管理中一种有效的辅助治疗方法。本研究的目的是评估在多学科康复计划中增加WBC干预对肥胖纤维肌痛患者样本的疼痛强度、抑郁症状、疾病影响、睡眠质量和基于表现的身体功能的影响。我们进行了一项随机对照试验，43名患有纤维肌痛和肥胖症的患者接受了多学科康复计划，其中一组在两周内额外接受了十次2分钟、温度为-110°C的WBC治疗，另一组没有。根据我们的结果，两周内进行十次WBC治疗产生了额外的益处。事实上，两组在康复后都报告了积极的变化；然而，接受WBC干预的组在疼痛严重程度、抑郁症状、疾病影响和睡眠质量方面有更大的改善。相反，在基于表现的身体功能方面，我们发现组间没有显著差异。我们的研究结果表明，WBC可能是一种有前景的辅助治疗方法，可改善纤维肌痛的关键方面，如疼痛、抑郁症状、疾病影响和睡眠质量差。
