Programa de Pós-Graduação em Ciências Veterinárias, Universidade Estadual do Ceará, Brazil.
Vet Parasitol. 2010 Oct 11;173(1-2):93-8. doi: 10.1016/j.vetpar.2010.06.004. Epub 2010 Jun 15.
The aim of this study was to evaluate the anthelmintic efficacy of Eucalyptus staigeriana essential oil (EsEO). The in vitro effects of EsEO were determined through the egg hatching test and the inhibition of larval development of Haemonchus contortus. The oil was subjected to acute and subacute toxicity rodents. The in vivo effects were determined through fecal egg count reduction test in goats. 1.35 and 5.4 mgml(-1) EsEO inhibited 99.27 and 99.20% H. contortus egg hatching and larval development. In subacute toxicity of EsEO, all parameters were found to be in the normal range, and histopathological analysis of organs did not present alterations. EsEO efficacy against goat gastrointestinal nematodes was 76.57% at 15th day after treatment. E. staigeriana essential oil showed in vitro and in vivo anthelmintic activity.
本研究旨在评估蓝桉精油（EsEO）的驱虫效果。通过卵孵化试验和抑制捻转血矛线虫幼虫发育来确定 EsEO 的体外作用。对该油进行了急性和亚急性毒性啮齿动物试验。通过山羊粪便卵计数减少试验确定体内作用。1.35 和 5.4 mgml(-1) EsEO 抑制 99.27%和 99.20%的捻转血矛线虫卵孵化和幼虫发育。在 EsEO 的亚急性毒性中，所有参数均在正常范围内，器官的组织病理学分析未显示出改变。在治疗后第 15 天，EsEO 对山羊胃肠道线虫的疗效为 76.57%。蓝桉精油显示出体外和体内驱虫活性。
