Department of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Biosens Bioelectron. 2010 Sep 15;26(1):279-84. doi: 10.1016/j.bios.2010.06.014. Epub 2010 Jun 22.
A non-enzymatic glucose (Glc) sensor was developed by potentiostatically electrodepositing metallic Cu nanocubes from a precursor solution onto vertically well-aligned multi-walled carbon nanotube arrays (MWCNTs). The electrochemical characteristics of the sensor were studied by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). The sensor shows significantly higher electrocatalytic activity to the oxidation of Glc in 0.1M NaOH alkaline solution after modification of Cu nanocubes than before. The sensor response is rapid (<1s) and highly sensitive (1096 μA mM(-1) cm(-2)) with a wide linear range (up to 7.5 mM) and low detection limit (1.0 μM at signal/noise ratio (S/N)=3); it also exhibits high stability and specificity to Glc and performs very well in detecting of Glc concentration in human blood serum.
一种非酶葡萄糖（Glc）传感器通过恒电位从前驱体溶液中在垂直取向的多壁碳纳米管阵列（MWCNTs）上电化学沉积金属 Cu 纳米立方体来制备。通过电化学阻抗谱（EIS）和循环伏安法（CV）研究了传感器的电化学特性。Cu 纳米立方体修饰后，传感器在 0.1M NaOH 碱性溶液中对 Glc 氧化的电催化活性显著提高。传感器响应快速（<1s）、灵敏度高（1096 μA mM(-1) cm(-2)）、线性范围宽（高达 7.5 mM）、检测限低（1.0 μM，信噪比（S/N）=3）；对 Glc 具有高稳定性和特异性，在检测人血清中的 Glc 浓度方面表现出色。
