Kanthaswamy Sree, Satkoski Jessica, Kou Alex, Malladi Venkat, Glenn Smith David
Department of Anthropology, University of California-Davis, Davis, CA, USA.
J Med Primatol. 2010 Aug;39(4):252-65. doi: 10.1111/j.1600-0684.2010.00430.x.
While rates of gene flow between rhesus and longtail macaque populations near their hybrid zone in Indochina have been quantified elsewhere, this study demonstrates that the inter-specific introgression is not limited to the Indochinese hybrid zone but is more geographically widespread.
Twelve rhesus and longtail macaque populations were analyzed using single nucleotide polymorphic (SNP) loci.
There is evidence for inter-specific admixture between Chinese rhesus and mainland longtails, with implications for genetic diversity both in the Chinese super-SPF population at the California National Primate Research Center and in other primate facilities. Eastern Chinese rhesus appeared more highly derived than western Chinese rhesus, and allele sharing between longtails and Chinese rhesus was not random with regard to geographic distance, but no significant nuclear genetic differences between eastern and western Chinese rhesus were detected among the 245 genic SNPs assayed.
The implications of this inter-specific admixture for the use of Chinese rhesus and mainland longtail in biomedical research should be considered.
虽然在其他地方已经对恒河猴和食蟹猴在印度支那杂交区域附近种群之间的基因流动速率进行了量化，但本研究表明种间基因渗入并不局限于印度支那杂交区域，而是在地理上分布更广。
使用单核苷酸多态性（SNP）位点对12个恒河猴和食蟹猴种群进行了分析。
有证据表明中国恒河猴和大陆食蟹猴之间存在种间混合，这对加利福尼亚国家灵长类动物研究中心的中国超级无特定病原体种群以及其他灵长类动物设施中的遗传多样性都有影响。中国东部恒河猴似乎比中国西部恒河猴进化程度更高，并且食蟹猴和中国恒河猴之间的等位基因共享并非与地理距离无关，但在所检测的245个基因SNP中，未检测到中国东部和西部恒河猴之间存在显著的核基因差异。
应考虑这种种间混合对中国恒河猴和大陆食蟹猴在生物医学研究中使用的影响。
