Unità Operativa di Neurologia dell'Azienda Sanitaria di Firenze, Ospedale Piero Palagi, Firenze, Italy.
Brain Stimul. 2010 Apr;3(2):119-23. doi: 10.1016/j.brs.2010.01.001. Epub 2010 Jan 29.
The stability of hand-held coil positioning with neuronavigated versus conventional transcranial magnetic stimulation (TMS) is still underinvestigated. Eleven operators naïve for neuronavigation were asked to position and maintain a figure-of-eight-shaped coil over a dipole probe placed within of a polystyrene reproduction of the human head and scalp, in correspondence of the right primary motor cortex. Ten monophasic magnetic pulses were delivered at 46% maximal stimulator output (MSO) in two different experimental conditions: (1) assisted by an optically tracked neuronavigational system; and (2) without neuronavigation. With neuronavigated stimulation, both standard deviation and coefficient of variation of the voltages induced in the dipole probe were significantly lower than without neuronavigation. Results were confirmed in four operators performing a longer-lasting experiment using 50 magnetic pulses in each condition, at an intensity of at 40% MSO. Findings show that optically tracked neuronavigation improves the stability of focal coil positioning.
手持线圈定位在神经导航与传统经颅磁刺激（TMS）下的稳定性仍有待研究。11 名对神经导航不熟悉的操作人员被要求在一个位于聚苯乙烯人头和头皮复制品内的偶极子探头上方定位并保持一个八字形线圈，对应于右初级运动皮层。在两种不同的实验条件下，以 46%最大刺激器输出（MSO）施加 10 个单相磁脉冲：（1）在光学跟踪神经导航系统的辅助下；和（2）没有神经导航。在神经导航刺激下，在偶极子探头中感应的电压的标准差和变异系数均明显低于无神经导航刺激。在四名操作人员进行了一项持续时间更长的实验中，在每种条件下使用 50 个磁脉冲，强度为 40%MSO，结果得到了证实。研究结果表明，光学跟踪神经导航可提高焦点线圈定位的稳定性。
