Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Fertil Steril. 2011 Jan;95(1):281-4. doi: 10.1016/j.fertnstert.2010.06.004. Epub 2010 Jul 15.
To determine the feasibility of performing in vivo magnetic resonance elastography (MRE) for uterine leiomyoma.
Pilot study.
Academic medical center.
PATIENT(S): Six subjects planning surgical excision of uterine leiomyomas.
INTERVENTION(S): MRE before planned surgery.
MAIN OUTCOME MEASURE(S): Achieving an appropriate phase signal-to-noise ratio (PSNR) in the leiomyoma to allow assessment of leiomyoma elasticity in kilopascals (kPa).
RESULT(S): MRE was successful in all subjects for uteri ranging from 100 to >1,000 g. Subjects had body mass indexes ranging from 23.0 to 38.0 kg/m2. Appropriate PSNRs, ranging from 5.45 to 42.28, were achieved for leiomyomas in all subjects. Mean elasticity of uterine leiomyomas ranged from 3.95 to 6.68 kPa.
CONCLUSION(S): MRE is a feasible technique for studying the in vivo mechanical properties of uterine leiomyomas and demonstrates significant heterogeneity in elasticity between lesions. Further work is necessary to optimize the technique and understand the clinical utility of this technique for women with uterine leiomyomas.
确定活体磁共振弹性成像（MRE）用于子宫肌瘤的可行性。
初步研究。
学术医疗中心。
6 名计划接受子宫肌瘤切除术的患者。
计划手术前进行 MRE。
在子宫肌瘤中获得适当的相位信噪比（PSNR），以评估子宫肌瘤的弹性（kPa）。
所有患者的子宫质量范围为 100 至>1000g 的 MRE 均成功完成。患者的体重指数范围为 23.0 至 38.0kg/m2。所有患者的子宫肌瘤均获得了适当的 PSNR（5.45 至 42.28）。子宫平滑肌瘤的平均弹性范围为 3.95 至 6.68kPa。
MRE 是一种可行的技术，可用于研究子宫平滑肌瘤的体内机械特性，并显示出病变之间的弹性存在显著异质性。需要进一步优化技术并了解该技术在患有子宫肌瘤的女性中的临床应用。
