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内镜乳头大球囊扩张治疗既往括约肌切开术患者复发性胆管结石。

Endoscopic papillary large balloon dilation for the treatment of recurrent bile duct stones in patients with prior sphincterotomy.

机构信息

Division of Gastroenterology, Department of Internal Medicine, Yeungnam University College of Medicine, 317-1 Daemyung 5-dong, Nam-gu, Daegu, 705-717, Korea.

出版信息

J Gastroenterol. 2010 Dec;45(12):1283-8. doi: 10.1007/s00535-010-0284-7. Epub 2010 Jul 16.

Abstract

BACKGROUND

Endoscopic sphincterotomy (EST) is a standard procedure for the removal of bile duct stones. However, additional EST may increase the risk of bleeding and perforation in patients with prior EST. Endoscopic papillary large balloon dilation (EPLBD) can be an alternative method for removing recurrent common bile duct stones with lower risk of bleeding and perforation. The aim of this study was to evaluate the therapeutic outcomes and complications of EPLBD in patients with recurrent common duct stones who underwent EST previously.

METHODS

Between January 2006 and August 2009, 70 patients with recurrent bile duct stones who had a history of EST were studied retrospectively. All patients underwent EPLBD without additional EST to enlarge the ampullary orifice. The size of the balloon for EPLBD was 12-18 mm and the duration of the balloon dilatation was 30-60 s.

RESULTS

Of the 70 patients, there were 24 patients (34.3%) with periampullary diverticula, 18 patients (25.7%) with hypertension, 4 patients (5.7%) with ischemic heart diseases, 2 patients (2.9%) with liver cirrhosis, and 1 patient (1.4%) with chronic kidney disease. Mean diameter of the stones was 12.5 ± 5.5 mm. Complete clearance of the duct was achieved in all patients and mechanical lithotripsy was needed in 1 patient (1.4%). Sixty-eight cases (97.1%) required only 1 session of ERCP to achieve complete ductal clearance. Mild pancreatitis occurred in 1 patient (2.3%), but there was no bleeding or perforation.

CONCLUSION

EPLBD is an effective and safe method for the treatment of recurrent common duct stones in patients with prior EST.

摘要

背景

内镜下括约肌切开术(EST)是一种标准的胆管结石去除方法。然而,对于有既往 EST 史的患者,额外的 EST 可能会增加出血和穿孔的风险。内镜下乳头大球囊扩张术(EPLBD)是一种替代方法,用于去除复发性胆总管结石,其出血和穿孔的风险较低。本研究旨在评估既往接受 EST 治疗的复发性胆总管结石患者行 EPLBD 的治疗效果和并发症。

方法

2006 年 1 月至 2009 年 8 月,回顾性分析了 70 例有既往 EST 史的复发性胆管结石患者。所有患者均行 EPLBD 治疗,无需额外的 EST 来扩大壶腹开口。EPLBD 中使用的球囊大小为 12-18mm,球囊扩张时间为 30-60s。

结果

70 例患者中,有 24 例(34.3%)有壶腹憩室,18 例(25.7%)有高血压,4 例(5.7%)有缺血性心脏病,2 例(2.9%)有肝硬化,1 例(1.4%)有慢性肾脏病。结石平均直径为 12.5±5.5mm。所有患者均完全清除胆管,1 例(1.4%)患者需要机械碎石。68 例(97.1%)仅需 1 次 ERCP 即可完全清除胆管。1 例(2.3%)发生轻度胰腺炎,但无出血或穿孔。

结论

EPLBD 是治疗既往接受 EST 治疗的复发性胆总管结石的有效且安全的方法。

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