Division of Pulmonary and Critical Care, Department of Medicine, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 222, Burlington, VT 05405, USA.
Crit Care Clin. 2010 Jul;26(3):501-14, ix. doi: 10.1016/j.ccc.2010.04.009.
Fish oil is rich in omega-3 fatty acids, which have been shown to be beneficial in multiple disease states that involve an inflammatory process. It is now hypothesized that omega-3 fatty acids may decrease the inflammatory response and be beneficial in critical illness. After a review of the mechanisms of omega-3 fatty acids in inflammation, research using enteral nutrition formulas and parenteral nutrition lipid emulsions fortified with fish oil were examined. The results of this research to date are inconclusive for both enteral and parenteral omega-3 fatty acid administration. More research is required before definitive recommendations can be made on fish oil supplementation in critical illness.
鱼油富含ω-3 脂肪酸，已被证明对涉及炎症过程的多种疾病状态有益。现在有人假设ω-3 脂肪酸可能会减轻炎症反应，并有益于危重病。在回顾了ω-3 脂肪酸在炎症中的作用机制后，研究了使用肠内营养配方和强化鱼油的肠外营养脂质乳剂。迄今为止，这方面的研究结果对于肠内和肠外给予ω-3 脂肪酸都没有定论。在对危重病患者补充鱼油提出明确建议之前，还需要进行更多的研究。
