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经内镜逆行胰胆管造影术(ERCP)置放胆管支架后的择期腹腔镜胆囊切除术

Elective laparoscopic cholecystectomy in the presence of common bile duct stent.

机构信息

Department of General Surgery, North Middlesex University Hospital, Sterling Way, London, N22 1XL, UK.

出版信息

Surg Endosc. 2011 Feb;25(2):429-36. doi: 10.1007/s00464-010-1185-9. Epub 2010 Jul 20.

DOI:10.1007/s00464-010-1185-9
PMID:20644963
Abstract

BACKGROUND

Endoscopic retrograde cholangiopancreatography (ERCP) is a common procedure done in patients with common bile duct (CBD) stones. Some clinicians insert a CBD stent at the time of ERCP. Such patients may then present for laparoscopic cholecystectomy (LC) with CBD stents in situ. The aim of this study was to examine the impact of the presence of a CBD stent on the outcome of elective LC.

METHODS

This was a case-controlled study conducted from January 2005 to June 2008. The patients were divided into three comparable groups: group 1, those having LC preceded by ERCP; group 2, those having LC preceded by ERCP and stent insertion; and group 3, those having LC alone.

RESULTS

Four hundred one LC procedures were performed, five of which were excluded (two had had previous upper abdominal surgery, two had isolated pancreatic stents, and one had the stent removed the day before surgery). Of the 396 patients studied, there were 31 patients in group 1, 35 patients in group 2, and 330 patients in group 3. The incidence of conversion, postoperative bile leak, operating time, and length of stay was significantly higher in Group 2 (p<0.05). The incidence of conversion increased with the duration of in-situ stent placement (Spearman correlation coefficient=0.34, p<0.05). There was one case of abandoned cholecystectomy, two cases of CBD erosion, one case of CBD injury, and two cases of in-hospital mortality, all involving patients in group 2 only.

CONCLUSIONS

We conclude that LC in the presence of CBD stents poses significant risk to patients, particularly if they are left in-situ for long periods of time. Caution should be exercised in stenting a CBD with an intact gallbladder, particularly in those awaiting cholecystectomy.

摘要

背景

内镜逆行胰胆管造影术(ERCP)是一种常见的治疗胆总管(CBD)结石的方法。一些临床医生在 ERCP 时会插入 CBD 支架。这些患者随后可能会出现 CBD 支架原位的腹腔镜胆囊切除术(LC)。本研究旨在检查 CBD 支架的存在对择期 LC 结果的影响。

方法

这是一项从 2005 年 1 月至 2008 年 6 月进行的病例对照研究。患者分为三组:组 1,LC 前接受 ERCP;组 2,LC 前接受 ERCP 和支架置入;组 3,仅接受 LC。

结果

共进行了 401 例 LC 手术,其中 5 例被排除(2 例有上腹部手术史,2 例有单纯胰腺支架,1 例支架在手术前一天取出)。在 396 例研究患者中,组 1 有 31 例,组 2 有 35 例,组 3 有 330 例。与组 3 相比,组 2 的中转率、术后胆漏、手术时间和住院时间明显较高(p<0.05)。在位支架放置时间与中转率呈正相关(Spearman 相关系数=0.34,p<0.05)。有 1 例胆囊切除术被放弃,2 例 CBD 侵蚀,1 例 CBD 损伤,2 例院内死亡,均发生在组 2 患者中。

结论

我们得出结论,CBD 支架存在时行 LC 会给患者带来显著风险,尤其是如果 CBD 支架长期在位。在存在完整胆囊的情况下对 CBD 进行支架置入时应慎重,尤其是在等待胆囊切除术的患者中。

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