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从肾蕨骨保护部位中提取的苯丙素和类黄酮。

Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortunei.

机构信息

Musculoskeletal Research Laboratory, Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, SAR, China.

出版信息

Nat Prod Res. 2010 Aug;24(13):1206-13. doi: 10.1080/14786410902991860.

DOI:10.1080/14786410902991860
PMID:20645207
Abstract

A new phenylpropanoid (1), 12-O-caffeoyl-12-hydroxyldodecanoic acid, and a new chalcone (2), 3'-lavandulyl-4-methoxyl-2,2',4',6'-tetrahydroxylchalcone, together with eight known compounds including one chalcone (3), five flavanones (4-8) and two flavonols (9, 10), have been isolated from one of the osteoprotective fractions of Drynaria fortunei (Kunze) J. Sm., which is used as a folk medicine for the treatment of osteoporosis. All these compounds were found for the first time from the genus Drynaria. The structures of the new compounds were elucidated on the basis of spectroscopic analysis.

摘要

从具有护骨作用的药用蕨类植物狗脊(Drynaria fortunei (Kunze) J. Sm.)的一个部位中分离得到了一个新的苯丙素类化合物(1),12-O-咖啡酰基-12-羟基十二烷酸,和一个新的查尔酮(2),3'-薰衣草基-4-甲氧基-2,2',4',6'-四羟基查尔酮,以及包括一个查尔酮(3)、五个黄烷酮(4-8)和两个黄酮醇(9,10)在内的另外 8 个已知化合物。狗脊被民间用于治疗骨质疏松症。这些化合物均为首次从该属植物中分离得到。新化合物的结构是基于光谱分析确定的。

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