Dept. of Respiratory Medicine, Allergy and Thoracic Surgery, University Hospitals of Leicester NHS trust, Glenfield Hospital, Leicester, United Kingdom.
Respir Med. 2010 Oct;104(10):1473-81. doi: 10.1016/j.rmed.2010.04.024. Epub 2010 Jul 21.
Patients with Chronic Heart Failure (CHF) develop similar symptoms of exertional breathlessness and fatigue as patients with COPD. Although pulmonary (exercise based) rehabilitation (PR) is an integral part of the management of COPD, the potential for exercise rehabilitation (ER) to assist patients with CHF may not be as readily appreciated. We investigated whether combined ER for patients with CHF and COPD was feasible and effective using the model of PR.
57 patients with CHF were randomized 2:1 to 7 weeks ER (CHF-ER) or 7 weeks of usual care (CHF-UC). As a comparator 55 patients with COPD were simultaneously recruited to the same ER program (COPD-ER). The primary outcome measure was the Incremental Shuttle Walk Test (ISWT) and the secondary outcome measures were the Endurance Shuttle Walk Test (ESWT), isometric quadriceps strength and health status.
27 CHF and 44 COPD patients completed ER and 17 patients with CHF completed UC. The CHF-ER group made significant improvements, compared to CHF-UC, in the mean (95%CI) ISWT distance; 62(35-89)m vs -6(-11 to 33)m p < 0.001. The CHF-ER group also made statistically significant improvements in health status. The improvements in exercise performance and health status were similar between patients with CHF and COPD, treated with ER.
Patients with CHF who undergo ER improve similarly in their exercise performance and health status to COPD. Combined training programs for COPD and CHF are effective and feasible, such that service provision could be targeted around common disability rather than the primary organ disease.
患有慢性心力衰竭(CHF)的患者会出现与 COPD 患者类似的呼吸困难和疲劳症状。虽然肺康复(PR)是 COPD 管理的重要组成部分,但运动康复(ER)对 CHF 患者的潜在辅助作用可能并不容易被察觉。我们使用 PR 模型研究了 CHF 和 COPD 患者联合 ER 的可行性和有效性。
57 例 CHF 患者被随机分为 2:1 接受 7 周 ER(CHF-ER)或 7 周常规护理(CHF-UC)。同时,招募了 55 例 COPD 患者作为对照组,进行相同的 ER 项目(COPD-ER)。主要结局测量指标为递增式踏步测试(ISWT),次要结局测量指标为耐力式踏步测试(ESWT)、等长股四头肌力量和健康状况。
27 例 CHF 和 44 例 COPD 患者完成了 ER,17 例 CHF 患者完成了 UC。与 CHF-UC 相比,CHF-ER 组的平均(95%CI)ISWT 距离有显著改善;62(35-89)m 比-6(-11 到 33)m,p < 0.001。CHF-ER 组在健康状况方面也有统计学意义的改善。接受 ER 治疗的 CHF 和 COPD 患者的运动表现和健康状况改善相似。
接受 ER 的 CHF 患者在运动表现和健康状况方面的改善与 COPD 患者相似。针对 COPD 和 CHF 的联合训练计划是有效且可行的,因此服务提供可以围绕共同的残疾而不是主要的器官疾病进行。