John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.
J Cataract Refract Surg. 2010 Aug;36(8):1398-420. doi: 10.1016/j.jcrs.2010.06.003.
Glistenings are fluid-filled microvacuoles that form within the intraocular lens (IOL) optic when the IOL is in an aqueous environment. They are observed in all types of IOLs but have been mainly associated with hydrophobic acrylic IOLs. Experimental and clinical studies suggest the various hydrophobic acrylic IOLs on the market exhibit different tendencies toward glistenings. Factors influencing glistening formation include IOL material composition, manufacturing technique, packaging, associated conditions such as glaucoma or those leading to breakdown of the blood-aqueous barrier, as well as concurrent use of ocular medications. Although the impact of glistenings on postoperative visual function and the evolution of glistenings in the late postoperative period remain controversial, IOL explantation has rarely been reported. The phenomenon of surface light scattering has also been described in association with hydrophobic acrylic IOLs. Its mechanism of formation is controversial but may be related to long-term phase separation water near the IOL surface, although not seen as microvacuoles.
The author has no financial or proprietary interest in any material or method mentioned.
当眼内透镜（IOL）处于水相环境时，在 IOL 光学部中形成充满液体的微小空泡，称为闪光。在所有类型的 IOL 中都可以观察到闪光，但主要与疏水性丙烯酸 IOL 有关。实验和临床研究表明，市场上各种疏水性丙烯酸 IOL 对闪光的形成表现出不同的倾向。影响闪光形成的因素包括 IOL 材料组成、制造技术、包装、青光眼等相关情况或导致血-房水屏障破裂的情况，以及同时使用眼部药物。尽管闪光对术后视觉功能的影响以及术后晚期闪光的演变仍存在争议，但很少有报道称需要取出 IOL。也有描述与疏水性丙烯酸 IOL 相关的表面光散射现象。其形成机制存在争议，但可能与长期存在于 IOL 表面附近的相分离水有关，尽管未观察到微空泡。
作者没有任何与文中提到的材料或方法相关的财务或所有权利益。
