粘菌找到了新的角色来建模。
Dictyostelium finds new roles to model.
机构信息
College of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.
出版信息
Genetics. 2010 Jul;185(3):717-26. doi: 10.1534/genetics.110.119297.
Abstract
Any established or aspiring model organism must justify itself using two criteria: does the model organism offer experimental advantages not offered by competing systems? And will any discoveries made using the model be of wider relevance? This review addresses these issues for the social amoeba Dictyostelium and highlights some of the organisms more recent applications. These cover a remarkably wide gamut, ranging from sociobiological to medical research with much else in between.
摘要
任何既定或有抱负的模式生物都必须用两个标准来证明自己的合理性
该模式生物是否提供了竞争系统所没有提供的实验优势？并且，使用该模型所做出的任何发现是否具有更广泛的相关性？本文针对社会变形虫 Dictyostelium 探讨了这些问题，并强调了该生物最近的一些应用。这些应用涵盖了从社会生物学到医学研究的广泛范围，其间还有许多其他领域。
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Activated cAMP receptors switch encystation into sporulation.激活的环磷酸腺苷（cAMP）受体将包囊化转变为孢子形成。
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