Carney L J, Chermak G D
Department of Speech and Hearing Sciences, Washington State University, Pullman 99164-2420.
J Commun Disord. 1991 Apr;24(2):123-34. doi: 10.1016/0021-9924(91)90016-c.
Alcohol is a teratogen known to have deleterious effects on the developing embryo and fetus. Language deficits secondary to central nervous system dysfunction are among the sequelae of Fetal Alcohol Syndrome (FAS). Limited information is available regarding the language deficits associated with FAS, particularly among the population of American Indians in whom FAS is highly prevalent. The TOLD-P and TOLD-I were administered to 27 American Indian children: 10 with FAS and 17 normally developing control subjects. Pure-tone screening, immittance measurement, and vision screening preceded language testing. The older FAS children presented syntactic deficits while the younger FAS subjects presented more global language deficits.
酒精是一种已知对发育中的胚胎和胎儿有有害影响的致畸物。中枢神经系统功能障碍继发的语言缺陷是胎儿酒精综合征(FAS)的后遗症之一。关于与FAS相关的语言缺陷的信息有限,尤其是在FAS高度流行的美国印第安人群体中。对27名美国印第安儿童进行了皮博迪图片词汇测验修订版(TOLD-P)和皮博迪个别词汇测验修订版(TOLD-I):10名患有FAS,17名发育正常的对照受试者。在语言测试之前进行了纯音筛查、声导抗测量和视力筛查。年龄较大的FAS儿童存在句法缺陷,而年龄较小的FAS受试者存在更全面的语言缺陷。