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Zenker 憩室的内镜治疗:7 年经验的结果。

Endoscopic treatment of Zenker diverticulum: results of a 7-year experience.

机构信息

Department of Upper GI and Laparoscopic Surgery, Peter-Lougheed Center, Calgary, Alberta, Canada.

出版信息

J Am Coll Surg. 2010 Aug;211(2):239-43. doi: 10.1016/j.jamcollsurg.2010.04.011.

Abstract

BACKGROUND

Zenker diverticulum (ZD) is a rare disease usually seen in elderly patients who present with symptoms of worsening dysphagia and regurgitation. Although open surgical approach is still the standard management for symptomatic patients, the endoscopic technique has evolved as an alternative approach, especially for highly morbid patients. We are reporting our experience for treating ZD using endoscopic needle-knife papillotome.

STUDY DESIGN

A total of 18 patients with a mean age of 80 years (range 68 to 91 years) were included in our prospective cohort study. All patients underwent endoscopic cricopharyngeal myotomy for symptomatic ZD using needle-knife papillotome at Brandon Regional Health Centre during a 7-year period. Mean follow-up was 27.5 months. A dysphagia score system from 0 (no dysphagia) to 4 (severe dysphagia) was used. All patients' baseline characteristics, pre- and postoperative symptoms, operative time, time to oral intake, length of hospital stay, recurrence of symptoms, and complications were analyzed.

RESULTS

Dysphagia score and regurgitation symptoms improved substantially after treatment. Mean operative time was 28.4 minutes. Oral intake was resumed within 24 hours in all but 1 patient. Hospital stay for the majority was 24 to 48 hours. Only 1 patient had a microperforation treated conservatively and 2 patients had re-do procedures for persistence of dysphagia.

CONCLUSIONS

Endoscopic cricopharyngeal myotomy using needle-knife papillotome is an effective approach to manage ZD for highly morbid patients. It is minimally invasive, decreases anesthetic time, shortens hospital stay, and has a low complication rate.

摘要

背景

Zenker 憩室(ZD)是一种罕见疾病,通常见于老年患者,其症状为吞咽困难和反流加重。虽然开放性手术仍然是有症状患者的标准治疗方法,但内镜技术已作为一种替代方法发展起来,特别是对于高度病态的患者。我们报告了使用内镜针刀切开刀治疗 ZD 的经验。

研究设计

在 7 年期间,共有 18 名平均年龄为 80 岁(68 至 91 岁)的患者在布兰登地区健康中心接受了内镜环咽肌切开术治疗有症状的 ZD。使用针刀切开刀。平均随访时间为 27.5 个月。使用从 0(无吞咽困难)到 4(严重吞咽困难)的吞咽困难评分系统。分析了所有患者的基线特征、术前和术后症状、手术时间、开始口服摄入的时间、住院时间、症状复发和并发症。

结果

治疗后吞咽困难评分和反流症状明显改善。平均手术时间为 28.4 分钟。除 1 例患者外,所有患者均在 24 小时内恢复口服摄入。大多数患者的住院时间为 24 至 48 小时。只有 1 例患者发生微小穿孔,经保守治疗,2 例患者因吞咽困难持续存在而进行了再次手术。

结论

使用针刀切开刀行内镜环咽肌切开术是治疗高度病态患者 ZD 的有效方法。它具有微创性,可减少麻醉时间,缩短住院时间,并发症发生率低。

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