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ω-3脂肪酸在心血管疾病中的有益作用。

Beneficial effects of omega-3 fatty acids in cardiovascular disease.

作者信息

Freeman Lisa M

机构信息

Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.

出版信息

J Small Anim Pract. 2010 Sep;51(9):462-70. doi: 10.1111/j.1748-5827.2010.00968.x. Epub 2010 Jul 29.

DOI:10.1111/j.1748-5827.2010.00968.x
PMID:20673293
Abstract

There is a large body of evidence supporting beneficial effects of omega-3 fatty acids for both primary and secondary prevention of cardiac disease in people. However, evidence is increasing for the use of omega-3 fatty acids in dogs with cardiac disease as well. Omega-3 fatty acids' anti-inflammatory and anti-arrhythmic effects may be beneficial in managing the loss of lean body mass and arrhythmias that are common in heart failure. However, omega-3 fatty acids also may have positive effects on myocardial energy metabolism, endothelial function, heart rate and blood pressure, and immune function. Additional research is needed to determine optimal indications, doses and formulations for dogs and cats with cardiac disease.

摘要

有大量证据支持ω-3脂肪酸对人类心脏病一级和二级预防的有益作用。然而,ω-3脂肪酸用于患有心脏病的犬类的证据也在增加。ω-3脂肪酸的抗炎和抗心律失常作用可能有助于控制心力衰竭中常见的瘦体重减少和心律失常。然而,ω-3脂肪酸也可能对心肌能量代谢、内皮功能、心率和血压以及免疫功能产生积极影响。需要进一步研究以确定患有心脏病的犬猫的最佳适应症、剂量和制剂。

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