两份脑膜炎奈瑟菌 C 群临床分离株的基因组草图序列。
Draft genome sequences of two Neisseria meningitidis serogroup C clinical isolates.
机构信息
Department of Histology, Microbiology, and Medical Biotechnologies, University of Padua, Via A. Gabelli, 63-35121 Padua, Italy.
出版信息
J Bacteriol. 2010 Oct;192(19):5270-1. doi: 10.1128/JB.00789-10. Epub 2010 Jul 30.
Abstract
Neisseria meningitidis is a human-specific pathogen known for its capability to cause sepsis and meningitis. Here we report the availability of 2 draft genome sequences obtained from patients infected during the same epidemic outbreak. Both bacterial isolates belong to serogroup C, but their genome sequences show local and remarkable differences compared with each other or with the reference genome of strain FAM18.
摘要
脑膜炎奈瑟菌是一种专门感染人类的病原体，其能够引起败血症和脑膜炎。在此，我们报告了从同一疫情爆发期间感染的患者中获得的 2 个草案基因组序列。这两种细菌分离株均属于 C 群血清型，但与参考菌株 FAM18 相比，它们的基因组序列存在局部和显著差异。
相似文献
1
Draft genome sequences of two Neisseria meningitidis serogroup C clinical isolates.两份脑膜炎奈瑟菌 C 群临床分离株的基因组草图序列。
J Bacteriol. 2010 Oct;192(19):5270-1. doi: 10.1128/JB.00789-10. Epub 2010 Jul 30.
2
Whole-Genome Characterization of Epidemic Neisseria meningitidis Serogroup C and Resurgence of Serogroup W, Niger, 2015.2015年，尼日利亚流行性脑膜炎奈瑟菌C群的全基因组特征及W群的再现
Emerg Infect Dis. 2016 Oct;22(10):1762-1768. doi: 10.3201/eid2210.160468.
3
Insight into proteomic investigations of Neisseria meningitidis serogroup C strain L91543 from analysis of its genome sequence.通过对脑膜炎奈瑟菌C群菌株L91543基因组序列的分析洞察其蛋白质组学研究
FEMS Microbiol Lett. 2015 May;362(9). doi: 10.1093/femsle/fnv055. Epub 2015 Apr 6.
4
Whole genome typing of the recently emerged Canadian serogroup W Neisseria meningitidis sequence type 11 clonal complex isolates associated with invasive meningococcal disease.对近期出现的与侵袭性脑膜炎球菌病相关的加拿大血清群 W 奈瑟菌 11 型克隆复合体分离株的全基因组分型。
Int J Infect Dis. 2018 Apr;69:55-62. doi: 10.1016/j.ijid.2018.01.019. Epub 2018 Feb 4.
5
Characterization of serogroup C meningococci isolated from 14 provinces of China during 1966-2005 using comparative genomic hybridization.利用比较基因组杂交技术对1966年至2005年间从中国14个省份分离出的C群脑膜炎奈瑟菌进行特征分析。
Sci China C Life Sci. 2007 Feb;50(1):1-6. doi: 10.1007/s11427-007-0016-2.
6
Deletion of fetA gene sequences in serogroup B and C Neisseria meningitidis isolates.B群和C群脑膜炎奈瑟菌分离株中fetA基因序列的缺失
J Clin Microbiol. 2007 Apr;45(4):1333-5. doi: 10.1128/JCM.02422-06. Epub 2007 Feb 7.
7
A New Sequence Type of Neisseria meningitidis Serogroup C Associated With a 2016 Meningitis Outbreak in Mali.一种与 2016 年马里脑膜炎爆发相关的 C 群脑膜炎奈瑟菌新型序列型。
J Infect Dis. 2019 Oct 31;220(220 Suppl 4):S190-S197. doi: 10.1093/infdis/jiz272.
8
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.通过对C群菌株FAM18的比较分析观察脑膜炎球菌的遗传变异机制。
PLoS Genet. 2007 Feb 16;3(2):e23. doi: 10.1371/journal.pgen.0030023. Epub 2006 Dec 21.
9
Multiple nucleotide substitutions in the Neisseria meningitidis serogroup C ctrA gene cause false-negative detection by real-time PCR.脑膜炎奈瑟菌 C 群 ctrA 基因的多个核苷酸取代导致实时 PCR 检测假阴性。
J Clin Microbiol. 2010 Aug;48(8):3016-8. doi: 10.1128/JCM.00103-10. Epub 2010 Jun 2.
10
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone.ST-4821复合体的特性分析，一种独特的脑膜炎奈瑟菌克隆。
Genomics. 2008 Jan;91(1):78-87. doi: 10.1016/j.ygeno.2007.10.004. Epub 2007 Nov 26.
引用本文的文献
1
Genomic comparative analysis and gene function prediction in infectious diseases: application to the investigation of a meningitis outbreak.基因组比较分析和传染病中的基因功能预测：在脑膜炎爆发调查中的应用。
BMC Infect Dis. 2013 Nov 19;13:554. doi: 10.1186/1471-2334-13-554.
本文引用的文献
1
Molecular mechanisms of complement evasion: learning from staphylococci and meningococci.补体逃避的分子机制：从葡萄球菌和脑膜炎奈瑟球菌中学习。
Nat Rev Microbiol. 2010 Jun;8(6):393-9. doi: 10.1038/nrmicro2366.
2
NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis.NeMeSys：缩小人类病原体脑膜炎奈瑟菌序列和功能之间差距的生物资源。
Genome Biol. 2009;10(10):R110. doi: 10.1186/gb-2009-10-10-r110. Epub 2009 Oct 9.
3
Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development.脑膜炎奈瑟菌逃避宿主免疫的机制及其对疫苗研发的影响。
Lancet Infect Dis. 2009 Jul;9(7):418-27. doi: 10.1016/S1473-3099(09)70132-X.
4
Outbreak of serogroup C meningococcal disease in Veneto region, Italy.
Euro Surveill. 2008 Jan 10;13(2):8008.
5
Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis.疾病菌株与携带菌株的全基因组比较为脑膜炎奈瑟菌的毒力进化提供了见解。
Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3473-8. doi: 10.1073/pnas.0800151105. Epub 2008 Feb 27.
6
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone.ST-4821复合体的特性分析，一种独特的脑膜炎奈瑟菌克隆。
Genomics. 2008 Jan;91(1):78-87. doi: 10.1016/j.ygeno.2007.10.004. Epub 2007 Nov 26.
7
Epidemic meningitis, meningococcaemia, and Neisseria meningitidis.流行性脑膜炎、脑膜炎球菌血症和脑膜炎奈瑟菌
Lancet. 2007 Jun 30;369(9580):2196-2210. doi: 10.1016/S0140-6736(07)61016-2.
8
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.通过对C群菌株FAM18的比较分析观察脑膜炎球菌的遗传变异机制。
PLoS Genet. 2007 Feb 16;3(2):e23. doi: 10.1371/journal.pgen.0030023. Epub 2006 Dec 21.
9
A greedy algorithm for aligning DNA sequences.一种用于比对DNA序列的贪婪算法。
J Comput Biol. 2000 Feb-Apr;7(1-2):203-14. doi: 10.1089/10665270050081478.
10
Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491.脑膜炎奈瑟菌Z2491 A群菌株的完整DNA序列。
Nature. 2000 Mar 30;404(6777):502-6. doi: 10.1038/35006655.
Zotero 插件