Division of Nephrology, Emory University, Atlanta, GA 30322, USA.
J Am Soc Nephrol. 2010 Oct;21(10):1776-82. doi: 10.1681/ASN.2009121235. Epub 2010 Aug 5.
There is substantial geographic variability in both incident and prevalent arteriovenous fistula (AVF) use among patients with ESRD. This study examined the degree to which these variations associate with poverty in the county of a patient's treatment center. We performed a cross-sectional study including 28,135 patients treated by 1127 hemodialysis centers in five ESRD networks (16 states) between June 1, 2005 and May 31, 2006. We used the 2000 U.S. Census to categorize county-level poverty and ascertained incident AVF use from the Medicare CMS 2728 form. We calculated the 30-month slope of change in AVF prevalence from monthly facility reports collected between 2003 and 2005. More than 33% of treatment centers were located in high-poverty counties. County poverty inversely associated with incident AVF use (P for trend = 0.001). In contrast, substantial increases in prevalent AVF rates from 30.9 to 38.6% (P < 0.001) among treatment centers did not associate with county poverty (P = 0.9519). In conclusion, the concentration of poverty in the county where a treatment is located associates with incident AVF use by patients with ESRD but not with subsequent improvement in AVF use among prevalent patients. These results suggest that the Medicare ESRD program may mitigate poverty effects on AVF use.
在患有终末期肾病的患者中,动静脉瘘(AVF)的发生率和患病率在地理上存在很大差异。本研究考察了这些差异与患者治疗中心所在县的贫困程度之间的关联程度。我们进行了一项横断面研究,纳入了 2005 年 6 月 1 日至 2006 年 5 月 31 日期间,1127 个血液透析中心在五个终末期肾病网络(16 个州)中治疗的 28135 名患者。我们使用 2000 年美国人口普查数据对县一级的贫困情况进行分类,并从医疗保险 CMS 2728 表中确定动静脉瘘的新发情况。我们根据 2003 年至 2005 年期间每月从医疗机构报告中收集的数据,计算动静脉瘘患病率的 30 个月变化斜率。超过 33%的治疗中心位于高贫困县。县贫困与新发动静脉瘘使用呈负相关(趋势 P 值=0.001)。相反,治疗中心的动静脉瘘患病率从 30.9%大幅增加到 38.6%(P<0.001),与县贫困无关(P=0.9519)。总之,治疗地点所在县的贫困程度与终末期肾病患者新发动静脉瘘使用相关,但与普遍患者动静脉瘘使用的后续改善无关。这些结果表明,医疗保险终末期肾病计划可能减轻贫困对动静脉瘘使用的影响。