Nee Robert, Moon Deepti S, Jindal Rahul M, Hurst Frank P, Yuan Christina M, Agodoa Lawrence Y, Abbott Kevin C
Nephrology, Walter Reed National Military Medical Center, Bethesda, Md., USA.
Am J Nephrol. 2015;42(4):328-36. doi: 10.1159/000441804. Epub 2015 Nov 17.
The impact of socioeconomic factors on arteriovenous fistula (AVF) creation in hemodialysis (HD) patients is not well understood. We assessed the association of area and individual-level indicators of poverty and health care insurance on AVF use among incident end-stage renal disease (ESRD) patients initiated on HD.
In this retrospective cohort study using the United States Renal Data System database, we identified 669,206 patients initiated on maintenance HD from January 1, 2007 through December 31, 2012. We assessed the Medicare-Medicaid dual-eligibility status as an indicator of individual-level poverty and ZIP code-level median household income (MHI) data obtained from the 2010 United States Census. We conducted logistic regression of AVF use at start of dialysis as the outcome variable.
The proportions of dual-eligible and non-dual-eligible patients who initiated HD with an AVF were 12.53 and 16.17%, respectively (p<0.001). Dual eligibility was associated with significantly lower likelihood of AVF use upon initiation of HD (adjusted odds ratio (aOR) 0.91; 95% CI 0.90-0.93). Patients in the lowest area-level MHI quintile had an aOR of 0.97 (95% CI 0.95-0.99) compared to those in higher quintile levels. However, dual eligibility and area-level MHI were not significant in patients with Veterans Affairs (VA) coverage.
Individual- and area-level measures of poverty were independently associated with a lower likelihood of AVF use at the start of HD, the only exception being patients with VA health care benefits. Efforts to improve incident AVF use may require focusing on pre-ESRD care to be successful.
社会经济因素对血液透析(HD)患者动静脉内瘘(AVF)建立的影响尚未完全明确。我们评估了贫困地区和个体层面指标以及医疗保险与初次接受HD治疗的终末期肾病(ESRD)患者AVF使用情况之间的关联。
在这项使用美国肾脏数据系统数据库的回顾性队列研究中,我们确定了2007年1月1日至2012年12月31日期间开始接受维持性HD治疗的669206例患者。我们将医疗保险-医疗补助双重资格状态作为个体层面贫困的指标,并使用从2010年美国人口普查中获取的邮政编码区域层面家庭收入中位数(MHI)数据。我们以透析开始时AVF的使用情况作为结果变量进行逻辑回归分析。
以AVF开始HD治疗的双重资格患者和非双重资格患者的比例分别为12.53%和16.17%(p<0.001)。双重资格与HD开始时使用AVF的可能性显著降低相关(调整后的优势比(aOR)为0.91;95%置信区间为0.90-0.93)。与处于较高五分位数水平的患者相比,处于最低区域层面MHI五分位数的患者的aOR为0.97(95%置信区间为0.95-0.99)。然而,对于有退伍军人事务部(VA)保险的患者,双重资格和区域层面MHI并不显著。
个体层面和区域层面的贫困指标与HD开始时AVF使用可能性较低独立相关,唯一的例外是享有VA医疗保健福利的患者。要成功提高初次AVF的使用率,可能需要将重点放在ESRD前期护理上。