Zaĭtseva K K
Arkh Patol. 1991;53(2):72-5.
Review of the literature on the role of Helicobacter pylori (HP) in the patho- and morphogenesis of chronic gastritis (CG) type B, gastric ulcer (GU) and duodenal ulcer (DU) is presented. Various hypotheses of pathogenetic effect of HP, histologic and ultrastructural characteristics of changes in the gastric and duodenal mucosa in HP infection are presented. The majority of authors consider HP as a possible pathogenic factor in CG type B, GU and DU. However, there are works in which HP is regarded as a saprophyte or a secondary infection. This indicates a necessity of further studies.
本文对幽门螺杆菌(HP)在B型慢性胃炎(CG)、胃溃疡(GU)和十二指肠溃疡(DU)的发病机制和形态发生中的作用的文献进行了综述。文中介绍了HP致病作用的各种假说,以及HP感染时胃和十二指肠黏膜变化的组织学和超微结构特征。大多数作者认为HP是B型CG、GU和DU的可能致病因素。然而,也有一些研究将HP视为腐生菌或继发感染。这表明有必要进行进一步的研究。