中国东北地区农村儿童体内的环境六氯环己烷（HCH）和滴滴涕（DDT）暴露情况。
Exposure to environmental hexachlorocyclohexane (HCH) and dichlorodiphenyltrichloroethane (DDT) among rural children in north eastern China.
机构信息
Department of Hygienic Toxicology, College of Public Health, Harbin Medical University, 157 BaoJian Road, Harbin, Heilongjiang, China.
出版信息
Biomed Environ Sci. 2010 Jun;23(3):230-3. doi: 10.1016/S0895-3988(10)60057-8.
OBJECTIVE
To assess HCH and DDT exposure levels and associated risk factors among 262 children aged 6-10 years in a northeastern rural area of China between April and May of 2008.
METHODS
Eight HCH and DDT metabolites in serum samples were monitored by gas chromatography. A questionnaire was administered to identify the sources of pesticides in children' serum samples.
RESULTS
At least one pesticide metabolite was detected in 81.7% of the tested children. Higher amounts of pp'DDD were detected in 50% of them. Children's age and their father's occupation as farmers, together with not changing work clothes after work, were the main risk factors for HCH and DDT exposure among them.
CONCLUSION
Children living in rural areas are experiencing multiple sources of organochlorine pesticide exposure. These pesticides may have been retained in the environment for a long period of time.
目的
评估 2008 年 4 月至 5 月期间东北地区 262 名 6-10 岁儿童的 HCH 和滴滴涕接触水平及相关危险因素。
方法
采用气相色谱法检测血清样本中的 8 种 HCH 和滴滴涕代谢物。通过问卷调查确定儿童血清样本中农药的来源。
结果
81.7%的受试儿童至少检测到一种农药代谢物。其中 50%的儿童检测到较高水平的 pp'DDD。儿童的年龄和其父亲是农民的职业，以及工作后不更换工作服，是儿童 HCH 和滴滴涕接触的主要危险因素。
结论
生活在农村地区的儿童正在经历多种有机氯农药的接触。这些农药可能在环境中长时间存在。
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