Seo Jong Keun, Lee Hyun Jae, Lee Deborah, Choi Joon Hee, Sung Ho-Suck
Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea.
Ann Dermatol. 2010 Aug;22(3):323-5. doi: 10.5021/ad.2010.22.3.323. Epub 2010 Aug 5.
Lichen planus pigmentosus (LPP) is chronic pigmentary disorder that shows diffuse or reticulated hyperpigmented, dark brown macules on the sun-exposed areas such as the face, neck and other flexural folds. Clinically, it is different from classical lichen planus because LPP has a longer clinical course and it manifests with dark brown macules. In case of LPP, involvement of the scalp, nail or mucosal area is rare. The histopathological findings of the lesions show an atrophic epidermis, the presence of melanophages and a vacuolar alteration of the basal cell layer with a sparse lymphohistiocytic lichenoid infiltration. Although there have been a few reports of LPP, there have only 3 cases of linear LPP along the lines of Blaschko in the Korean dermatologic literature. Our patient had lesions on the neck and chin with a linear pattern. In this report, we describe a very rare case of LPP with a linear distribution related to Blaschko's lines on the neck and chin areas.
色素性扁平苔藓(LPP)是一种慢性色素沉着性疾病,在面部、颈部等暴露于阳光下的部位以及其他屈侧褶皱处出现弥漫性或网状色素沉着、深褐色斑疹。临床上,它与经典扁平苔藓不同,因为LPP病程较长,表现为深褐色斑疹。LPP累及头皮、指甲或黏膜区域的情况罕见。病变的组织病理学表现为表皮萎缩、存在噬黑素细胞以及基底细胞层空泡样改变,伴有稀疏的淋巴细胞组织细胞样苔藓样浸润。尽管已有一些关于LPP的报道,但在韩国皮肤科文献中仅有3例沿Blaschko线分布的线状LPP病例。我们的患者颈部和下巴出现呈线状分布的病变。在本报告中,我们描述了一例极为罕见的颈部和下巴区域与Blaschko线相关的线状分布的LPP病例。