School of Pharmacy/Social Pharmacy, Campus of Kuopio, University of Eastern Finland, Finland.
Pharmacoepidemiol Drug Saf. 2010 Oct;19(10):1000-8. doi: 10.1002/pds.1963.
The aim of this study was to investigate the prevalence and concomitant use of prescription medicines and self-medication, including over-the-counter (OTC) medicines, vitamins, and complementary and alternative medicines (CAMs) among Finnish children aged under 12 years.
We carried out a nationwide postal survey of the use of medicines by a representative sample (n = 6000) of Finnish children aged under 12 years in spring 2007. A response rate of 67% (n = 4032) was achieved. The current use of prescription medicines and the use of OTC medicines, vitamins, and CAMs in the preceding 2 days were the main outcome measures.
In total, 17% of children had used prescription medicines and 50% some self-medication. The corresponding figures for OTC medicines, vitamins, and CAMs use were 17, 37, and 11%, respectively. Drugs for obstructive airway diseases were the most common prescription medicines, whereas analgesics and antipyretics, including non-steroidal-anti-inflammatory-medicines (NSAID), were the most common OTC medicines reported. Vitamin D was the most common vitamin, while fish oils and fatty acids were the most common CAMs used. Ten percent of the children had used prescription medicines and self-medication concomitantly.
Most of the children's medication consists of self-medication, and especially of vitamin use. However, also a considerable proportion had used prescription medicines, and a minority prescription medicines and self-medication concomitantly. In three of the cases, a combination of prescription and OTC medicine with a potential risk for interactions were found. Physicians should be aware of this wide use of self-medication when prescribing medicines.
本研究旨在调查芬兰 12 岁以下儿童中处方药物和自我用药(包括非处方(OTC)药物、维生素和补充剂和替代药物(CAM))的使用情况和同时使用情况。
我们于 2007 年春季对芬兰 12 岁以下儿童进行了一项全国性的代表性样本(n=6000)的药物使用邮政调查。实现了 67%的应答率(n=4032)。主要的观察结果是当前使用的处方药和前 2 天使用的 OTC 药物、维生素和 CAM 的使用情况。
共有 17%的儿童使用了处方药,50%的儿童使用了一些自我用药。相应的 OTC 药物、维生素和 CAM 的使用比例分别为 17%、37%和 11%。治疗气道阻塞性疾病的药物是最常见的处方药,而镇痛药和退烧药,包括非甾体抗炎药(NSAID),是最常见的报告的 OTC 药物。维生素 D 是最常见的维生素,而鱼油和脂肪酸是最常见的使用的 CAM。10%的儿童同时使用了处方药和自我用药。
大多数儿童的药物治疗由自我治疗组成,尤其是维生素的使用。然而,也有相当一部分儿童使用了处方药,少数儿童同时使用了处方药和自我用药。在三种情况下,都发现了同时使用处方药和 OTC 药物的情况,存在潜在的相互作用的风险。在开具药物时,医生应该意识到这种广泛的自我用药的使用情况。