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[一例直肠癌合并腹腔脓肿对尿嘧啶/替加氟(UFT)加口服亚叶酸钙(LV)治疗完全缓解的病例]

[A case of rectal cancer combined with intraperitoneal abscess responding completely to uracil/tegafur (UFT) plus oral leucovorin (LV) therapy].

作者信息

Yamada Kyouji, Narabashi Kiyoshi, Onoda Keiichirou, Honda Akeri, Hojyo Koudai, Kawashima Hatsuya, Hamaya Masahiro, Okamoto Norihiko, Noda Shinichiro, Kaneko Hideaki, Yokote Kunio

机构信息

Dept. of Gastroenterological and General Surgery, St. Marianna University School of Medicine.

出版信息

Gan To Kagaku Ryoho. 2010 Aug;37(8):1587-90.

PMID:20716893
Abstract

The patient was a 55-year-old man who complained of lower abdominal pain and fever, and was admitted to an emergency clinic. His diagnosis was rectal perforation combined with intraperitoneal abscess. Because his condition was in the preseptic state, an emergency operation was performed for colostomy and abscess drainage. After operation, he was diagnosed with rectal cancer colonoscopically. He refused reoperation and selected an oral chemotherapy regimen (UFT+LV therapy). 18 months later, he underwent Hartmann's operation. Histologically, cancer cells were absent. Complete response to chemotherapy was confirmed. He is free from any sign of recurrence until now.

摘要

患者为一名55岁男性,主诉下腹部疼痛和发热,被收治入急诊诊所。他的诊断为直肠穿孔合并腹腔脓肿。由于其病情处于感染前期,遂进行了急诊手术,行结肠造口术和脓肿引流。术后,经结肠镜检查诊断为直肠癌。他拒绝再次手术,选择了口服化疗方案(优福定+亚叶酸钙疗法)。18个月后,他接受了哈特曼手术。组织学检查显示无癌细胞。证实化疗完全缓解。截至目前,他没有任何复发迹象。

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