Institut Curie, Centre de Recherche, Traffic, Signaling, and Delivery Laboratory, 75248 Paris Cedex 05, France.
Cell. 2010 Aug 20;142(4):507-10. doi: 10.1016/j.cell.2010.08.007.
Lipid segregation occurs in biological membranes, but how this plays into cellular processes like endocytosis has been unclear. Here, we discuss how the active or passive induction of lipid-protein domain formation in membranes can alter membrane mechanics and thus affect processes such as the generation of curvature, the scission of buds and tubules, and lipid sorting.
脂质分离发生在生物膜中，但这在胞吞等细胞过程中是如何发挥作用的还不清楚。在这里，我们讨论了如何主动或被动诱导膜中脂质-蛋白质域的形成，从而改变膜力学，进而影响曲率的产生、芽和小管的断裂以及脂质分选等过程。
