Viera Anthony J, Schmid Dorothee, Bostrom Susan, Yow Angie, Lawrence William, DuBard C Annette
Department of Family Medicine, University of North Carolina, Chapel Hill, NC, USA.
J Am Soc Hypertens. 2010 Sep-Oct;4(5):244-54. doi: 10.1016/j.jash.2010.07.003. Epub 2010 Aug 21.
Failure to adjust hypertension therapy despite elevated blood pressure (BP) levels is an important contributor to lack of BP control. One possible explanation is that small elevations above goal BP are not concerning to clinicians. BP levels farther above goal, however, should be more likely to prompt clinical action. We reviewed 1 year's worth of primary care records of 3742 North Carolina Medicaid recipients 21 years and older with hypertension (a total of 15,516 office visits) to examine variations in hypertension management stratified by level of BP above goal and the association of BP level above goal with documented antihypertensive medication change. Among the 53% of patients not at goal BP, 42% were within 10/5 mm Hg of goal; 11% had a BP 40/20 mm Hg or higher above goal. Higher level of BP above goal was independently associated with antihypertensive medication change. Compared with visits at which BP was less than 10/5 mm Hg above goal, the adjusted odds of medication change were 7.9 (95% Confidence Interval 6.2-10.2) times greater at visits when patients' BP was 40/20 mm Hg or higher above goal. However, even when BP was above goal at this level, treatment change occurred only 46% (95% Confidence Interval 40.2-51.8) of the time.
尽管血压(BP)水平升高,但未能调整高血压治疗方案是导致血压控制不佳的一个重要因素。一种可能的解释是,血压略高于目标值对临床医生来说并不值得担忧。然而,血压远高于目标值时,应该更有可能促使临床采取行动。我们回顾了北卡罗来纳州3742名21岁及以上患有高血压的医疗补助受助者(总共15516次门诊就诊)一年的初级保健记录,以研究按高于目标值的血压水平分层的高血压管理差异,以及高于目标值的血压水平与记录在案的降压药物变化之间的关联。在血压未达目标值的患者中,42%的患者血压与目标值相差10/5 mmHg以内;11%的患者血压高于目标值40/20 mmHg或更多。高于目标值的血压水平越高,与降压药物变化独立相关。与血压高于目标值不到10/5 mmHg的就诊相比,当患者血压高于目标值40/20 mmHg或更多时,调整后的药物变化几率是前者的7.9倍(95%置信区间6.2 - 10.2)。然而,即使在这个水平上血压高于目标值,治疗改变也仅在46%(95%置信区间40.2 - 51.8)的时间发生。