Division of Hematology and Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Ann Behav Med. 2010 Dec;40(3):343-9. doi: 10.1007/s12160-010-9222-4.
Alcohol consumption is strongly associated with cigarette smoking in young adults.
The aim of this study was to evaluate the acceptability and estimate the magnitude of the effect of a novel-integrated smoking cessation and binge-drinking intervention for young adults compared with standard treatment control.
Participants were 41 young adult smokers (≥ 10 cigarettes per day) who regularly (≥ 2 times per month) binge drank who were randomly assigned to standard treatment (n = 19) involving eight individual treatment visits plus 8 weeks of nicotine patch therapy or the identical smoking cessation treatment integrated with a binge-drinking intervention (integrated intervention; n = 22).
Participants rated integrated intervention as highly acceptable as indicated by 100% of participants rating helpfulness as 5 on 5-point scale. Using an intent-to-treat analysis for tobacco abstinence, at both week 12 end of treatment and week 24 follow-up, more participants who received integrated intervention were biochemically confirmed abstinent from tobacco than those who received standard treatment (36% vs. 21% at week 12; 23% vs. 11% at week 24). At week 24, change from baseline in binge-drinking episodes, drinks consumed, and drinking days between treatment groups were similar (intent-to-treat analysis was not used for alcohol data).
Preliminary data support the intriguing possibility that integrated intervention may enhance smoking cessation and reduce binge drinking.
酒精消费与年轻人的吸烟行为密切相关。
本研究旨在评估一种新的综合性戒烟和狂饮干预措施对年轻人的可接受性,并估计其与标准治疗对照相比的效果大小。
参与者为 41 名每天至少吸 10 支香烟的成年吸烟者,他们经常(每月至少 2 次)狂饮,被随机分配到标准治疗组(n=19),包括 8 次个体治疗访问和 8 周的尼古丁贴片治疗,或与狂饮干预相结合的相同戒烟治疗(综合干预组;n=22)。
参与者对综合干预的评价非常高,100%的参与者在 5 分制中对其帮助程度评为 5 分。使用意向性治疗分析对烟草戒断进行分析,在第 12 周治疗结束和第 24 周随访时,接受综合干预的参与者中,有更多的人在生物化学上戒除了烟草,而接受标准治疗的参与者则为 36%(第 12 周)和 23%(第 24 周)。在第 24 周,治疗组之间从基线开始的狂饮发作、饮酒量和饮酒天数的变化相似(未使用意向性治疗分析来评估酒精数据)。
初步数据支持了一个有趣的可能性,即综合干预可能会增强戒烟效果并减少狂饮。