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胶原蛋白片YCWM作为烧伤创面敷料的临床应用。

Clinical application of collagen sheet, YCWM, as a burn wound dressing.

作者信息

Yang J Y

机构信息

Linkou Burn Unit, Department of Plastic Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.

出版信息

Burns. 1990 Dec;16(6):457-61. doi: 10.1016/0305-4179(90)90077-a.

DOI:10.1016/0305-4179(90)90077-a
PMID:2073346
Abstract

In the Linkou Burn Unit, a recently developed new wound dressing derived from porcine skin was evaluated. This newly designed porcine dressing, called young collagenous wettable membrane (YCWM), was developed by the staff of the Department of Cellular and Molecular Biology of Chang Gung Memorial Hospital. Many specific characteristics, such as negligible antigenicity, semitransparency, sterilizability, good pain relief and low costs, have been associated with it. The results of a clinical trial on 59 wounds on 50 burn patients proved encouraging. Some disadvantages such as maceration and delayed eschar separation were noted. We conclude that YCWM is suitable for the treatment of the clean, dry donor sites and superficial partial skin loss burn wounds of non-infected, non-immunocompromised patients.

摘要

在林口烧伤病房,对一种最近研发的源自猪皮的新型伤口敷料进行了评估。这种新设计的猪皮敷料名为年轻胶原可湿性膜(YCWM),由长庚纪念医院细胞与分子生物学系的工作人员研发。它具有许多特性,如抗原性可忽略不计、半透明、可消毒、止痛效果好且成本低。对50名烧伤患者身上的59处伤口进行的临床试验结果令人鼓舞。不过也发现了一些缺点,如浸渍和焦痂分离延迟。我们得出结论,YCWM适用于治疗未感染、无免疫功能低下患者的清洁、干燥供皮区以及浅表部分皮肤缺失的烧伤伤口。

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Clinical application of collagen sheet, YCWM, as a burn wound dressing.胶原蛋白片YCWM作为烧伤创面敷料的临床应用。
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Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Oct 20;38(10):978-982. doi: 10.3760/cma.j.cn501120-20211123-00394.