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[关于粘毛旋覆花提取物的观察与研究]

[Observations and research on an extract of Inula viscosa Ait ].

作者信息

Lauro L, Rolih C

机构信息

Cattedra di Chimica, Facoltà di Medicina e Chirurgia, Università degli Studi di Genova.

出版信息

Boll Soc Ital Biol Sper. 1990 Sep;66(9):829-34.

PMID:2073383
Abstract

The folk medical tradition ascribes to Inula viscosa (a suffrutescent plant of Compositae widely spread along the Mediterranean basin) balsamic, antipyretic, antiphlogistic and antiseptic properties. Pharmacological test on rabbits, made hyperpyretic in laboratory, gave satisfactory antipyretic results. Gas chromatographical separation from a high-boiling fraction of seven azulenes, two of them identified as 1,4-dimethyl-azulene (about 50% and chamazulene (32%), confirmed the antiphlogistic action ascribed to the plant. By the present research (solvent extraction, thin layer chromatography and gas chromatography are described in detail) eucalyptol was identified in a fraction of essential oil obtained from fresh leaves of the plant. This datum supports the balsamic and antiseptic properties of Inula viscosa Ait.

摘要

民间医学传统认为土木香(一种广泛分布于地中海盆地的菊科半灌木植物)具有香脂、退热、消炎和防腐特性。对实验室致热的兔子进行的药理试验取得了令人满意的退热效果。从高沸点馏分中通过气相色谱分离出七种薁类化合物,其中两种被鉴定为1,4 - 二甲基薁(约50%)和天蓝烃(32%),证实了该植物具有消炎作用。通过本研究(详细描述了溶剂萃取、薄层色谱和气相色谱法),在从该植物新鲜叶子中获得的一部分精油中鉴定出了桉叶油素。这一数据支持了土木香的香脂和防腐特性。

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