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[关于粘毛旋覆花提取物的观察与研究]

[Observations and research on an extract of Inula viscosa Ait ].

作者信息

Lauro L, Rolih C

机构信息

Cattedra di Chimica, Facoltà di Medicina e Chirurgia, Università degli Studi di Genova.

出版信息

Boll Soc Ital Biol Sper. 1990 Sep;66(9):829-34.

PMID:2073383
Abstract

The folk medical tradition ascribes to Inula viscosa (a suffrutescent plant of Compositae widely spread along the Mediterranean basin) balsamic, antipyretic, antiphlogistic and antiseptic properties. Pharmacological test on rabbits, made hyperpyretic in laboratory, gave satisfactory antipyretic results. Gas chromatographical separation from a high-boiling fraction of seven azulenes, two of them identified as 1,4-dimethyl-azulene (about 50% and chamazulene (32%), confirmed the antiphlogistic action ascribed to the plant. By the present research (solvent extraction, thin layer chromatography and gas chromatography are described in detail) eucalyptol was identified in a fraction of essential oil obtained from fresh leaves of the plant. This datum supports the balsamic and antiseptic properties of Inula viscosa Ait.

摘要

民间医学传统认为土木香(一种广泛分布于地中海盆地的菊科半灌木植物)具有香脂、退热、消炎和防腐特性。对实验室致热的兔子进行的药理试验取得了令人满意的退热效果。从高沸点馏分中通过气相色谱分离出七种薁类化合物,其中两种被鉴定为1,4 - 二甲基薁(约50%)和天蓝烃(32%),证实了该植物具有消炎作用。通过本研究(详细描述了溶剂萃取、薄层色谱和气相色谱法),在从该植物新鲜叶子中获得的一部分精油中鉴定出了桉叶油素。这一数据支持了土木香的香脂和防腐特性。

相似文献

1
[Observations and research on an extract of Inula viscosa Ait ].[关于粘毛旋覆花提取物的观察与研究]
Boll Soc Ital Biol Sper. 1990 Sep;66(9):829-34.
2
Antifungal activity of essential oils from leaves and flowers of Inula viscosa (Asteraceae) by Apulian region.普利亚地区粘毛旋覆花(菊科)叶和花中精油的抗真菌活性
Parassitologia. 2002 Dec;44(3-4):153-6.
3
[On the constituents of Inula viscosa Ait. I. Essential oil content of azulenes].
Boll Chim Farm. 1968 Jun;107(6):370-82.
4
A glycosyl analogue of diacylglycerol and other antiinflammatory constituents from Inula viscosa.来自粘旋覆花的二酰基甘油糖基类似物及其他抗炎成分。
J Nat Prod. 1999 Apr;62(4):601-4. doi: 10.1021/np980132u.
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Inhibition of pro-inflammatory enzymes by inuviscolide, a sesquiterpene lactone from Inula viscosa.粘毛旋覆花中的倍半萜内酯inuviscolide对促炎酶的抑制作用。
Fitoterapia. 2007 Jun;78(4):329-31. doi: 10.1016/j.fitote.2007.03.005. Epub 2007 Apr 11.
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[Fungistatic activity of a sesquiterpene lactone (tomentosin) isolated from fresh Inula viscosa (Asteraceae) flowers from the Puglia region].[从普利亚地区新鲜旋覆花(菊科)花朵中分离出的倍半萜内酯(绒毛旋覆花素)的抑菌活性]
Parassitologia. 2001 Sep;43(3):117-21.
7
[Research on antifungal activity of flowers and leaves of Inula viscosa (Asteraceae)].[粘毛旋覆花(菊科)花和叶的抗真菌活性研究]
Parassitologia. 1999 Dec;41(4):579-82.
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[Pharmacological properties of inulicin, a sesquiterpene lactone from Japanese inula].[旋覆花内酯的药理特性,一种来自日本旋覆花的倍半萜内酯]
Farmakol Toksikol. 1981 Jul-Aug;44(4):463-7.
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A mechanistic approach to the in vivo anti-inflammatory activity of sesquiterpenoid compounds isolated from Inula viscosa.
Planta Med. 2001 Nov;67(8):726-31. doi: 10.1055/s-2001-18342.
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Evaluation of the wound healing effect of some Jordanian traditional medicinal plants formulated in Pluronic F127 using mice (Mus musculus).使用小鼠(小家鼠)对以普朗尼克F127配制的一些约旦传统药用植物的伤口愈合效果进行评估。
J Ethnopharmacol. 2007 Jan 3;109(1):104-12. doi: 10.1016/j.jep.2006.07.010. Epub 2006 Jul 14.

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Biosynthesis of gold nanoparticles using leaf extract of Dittrichia viscosa and in vivo assessment of its anti-diabetic efficacy.
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Clarifying the molecular mechanism of tomentosin‑induced antiproliferative and proapoptotic effects in human multiple myeloma via gene expression profile and genetic interaction network analysis.通过基因表达谱和遗传相互作用网络分析阐明土木香内酯诱导人多发性骨髓瘤细胞增殖抑制和促凋亡作用的分子机制。
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Extract Inhibits Growth of Colorectal Cancer Cells and Through Induction of Apoptosis.提取物通过诱导细胞凋亡抑制结肠癌细胞生长。
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Antiproliferative, antimicrobial and apoptosis inducing effects of compounds isolated from Inula viscosa.植物大蓟中分离得到的化合物的抗增殖、抗菌和诱导细胞凋亡作用。
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Evaluation of cytotoxicity and genotoxicity of Inula viscosa leaf extracts with Allium test.用大蒜试验评估旋覆花叶片提取物的细胞毒性和遗传毒性。
J Biomed Biotechnol. 2010;2010:189252. doi: 10.1155/2010/189252. Epub 2010 Jun 23.