沙特阿拉伯利雅得一家大学医院收治的葡萄膜炎患者的发病模式。

Patterns of uveitis in patients admitted to a University Hospital in Riyadh, Saudi Arabia.

机构信息

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Ocul Immunol Inflamm. 2010 Dec;18(6):424-31. doi: 10.3109/09273948.2010.502284. Epub 2010 Aug 25.

DOI:10.3109/09273948.2010.502284

PMID:20735294

Abstract

PURPOSE

To analyze clinical patterns, causes, and systemic disease associations among patients with uveitis admitted to King Abdulaziz University Hospital.

METHODS

The authors retrospectively reviewed the medical records of 351 patients (600 eyes).

RESULTS

The study subjects consisted of 183 (52.1%) males and 168 (47.9%) females, with a mean age of 39.9 ± 14.2 years at presentation. The most common anatomic diagnosis was panuveitis (68.6%), followed by posterior uveitis (12.7%), anterior uveitis (12.7%), and intermediate uveitis (6.0%). The most common identifiable specific diagnoses were presumed tuberculous uveitis (PTU) (28.2%), Vogt-Koyanagi-Harada (VKH) disease (19.4%), Behçet disease (BD) (12.5%), and toxoplasmosis (8.2%). After a mean follow-up period of 29.5 ± 22.1 months, 63.5% of the eyes achieved visual acuity of 20/40 or better. Eyes from patients with PTU had the worst final visual outcome.

CONCLUSIONS

The most common anatomic diagnosis was panuveitis. PTU, VKH disease, BD, and toxoplasmosis were the most frequent specific diagnoses.

摘要

目的

分析在阿卜杜勒阿齐兹国王大学医院就诊的葡萄膜炎患者的临床特征、病因和与全身性疾病的关系。

方法

作者回顾性分析了 351 例（600 只眼）患者的病历。

结果

研究对象包括 183 例（52.1%）男性和 168 例（47.9%）女性，就诊时的平均年龄为 39.9 ± 14.2 岁。最常见的解剖学诊断是全葡萄膜炎（68.6%），其次是后葡萄膜炎（12.7%）、前葡萄膜炎（12.7%）和中间葡萄膜炎（6.0%）。最常见的明确特定诊断是疑似结核性葡萄膜炎（PTU）（28.2%）、Vogt-Koyanagi-Harada（VKH）病（19.4%）、Behçet 病（BD）（12.5%）和弓形体病（8.2%）。在平均 29.5 ± 22.1 个月的随访后，63.5%的眼视力达到 20/40 或更好。PTU 患者的眼最终视力最差。