Department of Internal Medicine, Hôtel Dieu, Hospices Civils de Lyon, Lyon, France.
Ocul Immunol Inflamm. 2011 Aug;19(4):219-26. doi: 10.3109/09273948.2011.580071.
To describe uveitis clinical characteristics in the elderly.
Retrospective review of 91 patients at the age of 60 or more years at the authors' uveitis tertiary center over a 7-year period.
Uveitis in the elderly accounted for 30.1% of this population. Uveitis localization was anterior in 22.0% of patients, intermediate in 8.8%, posterior in 20.9%, while 41.7% patients presented with panuveitis. Sarcoidosis (37.4%) and idiopathic uveitis (36.3%) accounted for the majority of cases, whereas other diagnostic entities accounted for 26.3%. Panuveitis (41.7%) and sarcoidosis (37.4%) were detected at a significantly higher frequency than in the younger population. Contrarily, ankylosing spondylitis and established ophthalmological entities (pars planitis, Birdshot chorioretinopathy, Fuchs heterochromic cyclitis) were more common in patients younger than 60 years old.
In the authors' experience, sarcoidosis is the leading cause of uveitis in the elderly. Idiopathic uveitis and other specific entities account for less than two-thirds of cases.
描述老年人葡萄膜炎的临床特征。
对作者的葡萄膜炎三级中心 7 年来就诊的 91 名 60 岁及以上老年患者进行回顾性分析。
老年人葡萄膜炎占该人群的 30.1%。22.0%的患者为前葡萄膜炎，8.8%为中间葡萄膜炎，20.9%为后葡萄膜炎，41.7%的患者为全葡萄膜炎。结节病（37.4%）和特发性葡萄膜炎（36.3%）占大多数，其他诊断实体占 26.3%。全葡萄膜炎（41.7%）和结节病（37.4%）的检出率明显高于年轻人群。相反，强直性脊柱炎和已确立的眼部疾病（中间葡萄膜炎、鸟枪弹样脉络膜视网膜病变、Fuchs 异色性睫状体脉络膜炎）在 60 岁以下患者中更为常见。
根据作者的经验，结节病是老年人葡萄膜炎的主要原因。特发性葡萄膜炎和其他特定疾病不到三分之二。
