Department of Maternal and Pediatric Sciences, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, University of Milan, Milan 20122, Italy.
Pediatr Res. 2010 Dec;68(6):542-4. doi: 10.1203/PDR.0b013e3181f85a20.
Nutrition in early life, growth, and subsequent health over a lifetime are significantly interrelated. The aim of this study was to assess body composition changes in exclusively breast-fed infants from birth up to 6 mo of age. An observational, prospective, cohort study was conducted. Fifty-nine full-term, healthy, exclusively breast-fed infants underwent assessment of growth and body composition, using air-displacement plethysmograph (i.e. PEA POD) by Life Measurement, Inc. (Concord, CA). Body composition was assessed at birth, 2 wk, and 1, 2, 3, 4, 5, and 6 mo of age. Mean birth weight (g) and gestational age (wk) of the infants were 3170 ± 420 and 39.21 ± 1.29, respectively. Percentage of fat mass increased significantly over the first 4 mo (p < 0.001), both in boys and girls, with no differences detected between boys and girls at any time point. This article provides preliminary in-depth data on whole-body composition, in exclusively breast-fed infants during the first months of life. Further studies assessing larger sample sizes are desirable to develop reference body composition data.
生命早期的营养、生长以及随后一生的健康状况密切相关。本研究旨在评估纯母乳喂养婴儿从出生到 6 个月龄时的身体成分变化。这是一项观察性、前瞻性的队列研究。59 名足月、健康、纯母乳喂养的婴儿接受了使用空气置换体描记法（即 PEA POD）的生长和身体成分评估，该方法由 Life Measurement, Inc.（加利福尼亚州康科德）提供。身体成分在出生时、2 周、1、2、3、4、5 和 6 个月时进行评估。婴儿的平均出生体重（g）和胎龄（wk）分别为 3170±420 和 39.21±1.29。男孩和女孩的体脂肪百分比在前 4 个月显著增加（p<0.001），但在任何时间点男孩和女孩之间均未检测到差异。本文提供了有关纯母乳喂养婴儿在生命最初几个月内全身成分的初步深入数据。需要进一步研究更大的样本量来制定参考身体成分数据。
