King's College London, Thames Cancer Registry, 1st floor, Capital House, 42 Weston Street, London, UK.
Br J Cancer. 2010 Sep 28;103(7):1076-80. doi: 10.1038/sj.bjc.6605857. Epub 2010 Aug 24.
Breast cancer 5-year relative survival is low in the North East London Cancer Network (NELCN).
We compared breast cancer that was diagnosed during 2001-2005 with that in the rest of London.
North East London Cancer Network women more often lived in socioeconomic quintile 5 (42 vs 21%) and presented with advanced disease (11 vs 7%). Cox regression analysis showed the survival difference (hazard ratio: 1.27, 95% confidence interval (CI): 1.15-1.41) reduced to 1.00 (95% CI: 0.89-1.11) after adjustment for age, stage, socioeconomic deprivation, ethnicity and treatment. Major drivers were stage and deprivation. Excess mortality was in the first year.
Late diagnosis occurs in NELCN.
在伦敦东北部癌症网络(NELCN),乳腺癌 5 年相对生存率较低。
我们比较了 2001-2005 年诊断出的乳腺癌与伦敦其他地区的乳腺癌。
NELCN 的女性更多地生活在社会经济五分位数 5 (42%比 21%),并表现出晚期疾病(11%比 7%)。Cox 回归分析显示,调整年龄、分期、社会经济剥夺、种族和治疗因素后,生存差异(风险比:1.27,95%置信区间(CI):1.15-1.41)降至 1.00(95%CI:0.89-1.11)。主要驱动因素是分期和贫困。超额死亡率发生在第一年。
NELCN 存在晚期诊断。