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伦敦癌症网络中乳腺癌低 5 年相对生存率的调查。

Investigation of low 5-year relative survival for breast cancer in a London cancer network.

机构信息

King's College London, Thames Cancer Registry, 1st floor, Capital House, 42 Weston Street, London, UK.

出版信息

Br J Cancer. 2010 Sep 28;103(7):1076-80. doi: 10.1038/sj.bjc.6605857. Epub 2010 Aug 24.

DOI:10.1038/sj.bjc.6605857
PMID:20736945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2965868/
Abstract

BACKGROUND

Breast cancer 5-year relative survival is low in the North East London Cancer Network (NELCN).

METHODS

We compared breast cancer that was diagnosed during 2001-2005 with that in the rest of London.

RESULTS

North East London Cancer Network women more often lived in socioeconomic quintile 5 (42 vs 21%) and presented with advanced disease (11 vs 7%). Cox regression analysis showed the survival difference (hazard ratio: 1.27, 95% confidence interval (CI): 1.15-1.41) reduced to 1.00 (95% CI: 0.89-1.11) after adjustment for age, stage, socioeconomic deprivation, ethnicity and treatment. Major drivers were stage and deprivation. Excess mortality was in the first year.

CONCLUSION

Late diagnosis occurs in NELCN.

摘要

背景

在伦敦东北部癌症网络(NELCN),乳腺癌 5 年相对生存率较低。

方法

我们比较了 2001-2005 年诊断出的乳腺癌与伦敦其他地区的乳腺癌。

结果

NELCN 的女性更多地生活在社会经济五分位数 5 (42%比 21%),并表现出晚期疾病(11%比 7%)。Cox 回归分析显示,调整年龄、分期、社会经济剥夺、种族和治疗因素后,生存差异(风险比:1.27,95%置信区间(CI):1.15-1.41)降至 1.00(95%CI:0.89-1.11)。主要驱动因素是分期和贫困。超额死亡率发生在第一年。

结论

NELCN 存在晚期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5046/2965868/0a7a144dc61b/6605857f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5046/2965868/0a7a144dc61b/6605857f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5046/2965868/0a7a144dc61b/6605857f1.jpg

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Breast cancer survival in England, Norway and Sweden: a population-based comparison.英格兰、挪威和瑞典的乳腺癌生存情况:一项基于人群的比较。
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The size of the prize for earlier diagnosis of cancer in England.英格兰早期诊断癌症的奖励金额有多大。
Br J Cancer. 2009 Dec 3;101 Suppl 2(Suppl 2):S125-9. doi: 10.1038/sj.bjc.6605402.
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Inequalities in breast cancer stage at diagnosis in the Trent region, and implications for the NHS Breast Screening Programme.特伦特地区乳腺癌诊断分期的不平等现象及其对英国国民健康服务体系乳腺癌筛查计划的影响。
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