Department of Psychiatry and Behavioral Neuroscience, University of Chicago, USA.
J Child Psychol Psychiatry. 2011 Jan;52(1):47-55. doi: 10.1111/j.1469-7610.2010.02290.x. Epub 2010 Aug 25.
Diagnostic validity of oppositional defiant and conduct disorders (ODD and CD) for preschoolers has been questioned based on concerns regarding the ability to differentiate normative, transient disruptive behavior from clinical symptoms. Data on concurrent validity have accumulated, but predictive validity is limited. Predictive validity is critical to refuting the hypothesis that diagnosing ODD and CD in young children leads to pathologizing normal behavior. ODD and CD have emerged as gateway disorders to many forms of adult psychopathology. Establishing how early we can identify symptoms and disorders that herald poor prognosis is one of the most important goals for research on etiology and prevention.
Subjects were 3-5-year-old consecutive referrals to a child psychiatry clinic (n=123) and demographically matched children from a pediatric clinic (n=100). A diagnostic interview was used to assess DSM-IV ODD and CD in a prospective follow-up design from preschool to school age. Stability of ODD and CD diagnoses and level of impairment were tested as a function of preschool diagnosis.
Over 80% of preschoolers diagnosed with ODD and approximately 60% of preschoolers diagnosed with CD met criteria for the same disorder during follow-up. Impairment over time varied significantly as a function of stability of diagnosis across three years.
These results provide the first evidence of the predictive validity of DSM-IV ODD and CD in clinically referred preschool children. The findings challenge the assumption that symptoms of disruptive behavior disorders that occur during the preschool period tend to be transient.
基于对区分正常、短暂的破坏性行为与临床症状的能力的担忧,对立违抗性障碍和品行障碍(ODD 和 CD)在学龄前儿童中的诊断有效性受到了质疑。关于同时效度的数据已经积累起来,但预测效度有限。预测效度对于反驳这样一种假设至关重要,即对幼儿进行 ODD 和 CD 的诊断会导致将正常行为病态化。ODD 和 CD 已成为许多形式的成人精神病理学的入门障碍。确定我们何时能够识别预示预后不良的症状和障碍,是病因学和预防研究的最重要目标之一。
研究对象为连续转诊至儿童精神病学诊所的 3-5 岁儿童(n=123)和儿科诊所的年龄匹配儿童(n=100)。使用诊断访谈在学龄前至学龄期进行前瞻性随访设计,以评估 DSM-IV ODD 和 CD。ODD 和 CD 诊断的稳定性和损害程度作为学龄前诊断的函数进行测试。
超过 80%的被诊断为 ODD 的学龄前儿童和约 60%的被诊断为 CD 的学龄前儿童在随访期间符合同一障碍的标准。随着时间的推移,损害程度因三年间诊断的稳定性而异。
这些结果首次提供了 DSM-IV ODD 和 CD 在临床转诊的学龄前儿童中具有预测效度的证据。这些发现挑战了这样一种假设,即在学龄前期间出现的破坏性行为障碍的症状往往是短暂的。