Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA.
J Abnorm Psychol. 2012 May;121(2):352-9. doi: 10.1037/a0024340. Epub 2011 Jun 27.
The Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition (DSM-5) workgroup for disruptive behavior disorders is considering adopting a frequency threshold for symptoms of oppositional defiant disorder (ODD). In the present study, the impact of substituting the term "often" with a specific age-based frequency on impairment and prognosis among preschool children was tested in a longitudinal design. Mutually exclusive groups were created to identify children who met criteria for ODD based on a symptom threshold of "often," as in Diagnostic and Statistical Manual for Mental Disorders, Fourth Edition (DSM-4), and those that met criteria for ODD based on a threshold of "1-2 times per day," which approximated the proposal for DSM-5. Comparisons of these groups to each other and to nondiagnosed peers determined the impact of changing the symptom threshold on impairment and prognosis. Close to one-third of children who met DSM-4 criteria for ODD did not meet criteria under the alternative diagnosis; African American children were overrepresented in this group. Preschoolers who met DSM-4, but not the alternative criteria, had higher rates of ODD, conduct disorder (CD), and were more impaired than their nondiagnosed peers at baseline and follow-up. Preschoolers meeting DSM-4 criteria were less impaired than children meeting the alternative ODD criteria at baseline according to parent, but not according to teacher report. No differences could be detected between those meeting DSM-4 and those meeting the alternative criteria in rate of ODD, CD, or impairment at follow-up. Among clinically referred preschool children, changing the symptom threshold for ODD could result in a sizable group of children who would no longer meet diagnostic criteria, despite demonstrating significant morbidity concurrently and prospectively.
《精神障碍诊断与统计手册》(第五版)(DSM-5)破坏性行为障碍工作组正在考虑为对立违抗性障碍(ODD)采用症状频率阈值。在本研究中,采用一种基于年龄的特定频率替代术语“经常”,以测试其对学龄前儿童损伤和预后的影响,研究采用纵向设计。创建互斥组以识别符合 DSM-4 标准的 ODD 儿童,这些儿童的症状标准为“经常”,而符合 DSM-5 标准的 ODD 儿童的症状标准为“每天 1-2 次”。将这些组彼此进行比较,并与未诊断的同龄人进行比较,以确定改变症状阈值对损伤和预后的影响。接近三分之一符合 DSM-4 标准的 ODD 儿童不符合替代诊断标准;在该组中,非洲裔美国儿童比例过高。符合 DSM-4 但不符合替代标准的学龄前儿童的 ODD、品行障碍(CD)的发生率更高,与未诊断的同龄人相比,在基线和随访时的损伤程度更高。符合 DSM-4 标准的学龄前儿童与符合替代标准的儿童相比,在基线时根据家长报告显示的损伤程度较高,但根据教师报告显示的损伤程度较低。在随访时,符合 DSM-4 标准和符合替代标准的儿童在 ODD、CD 或损伤发生率方面没有差异。在临床上转诊的学龄前儿童中,改变 ODD 的症状阈值可能会导致相当一部分儿童不再符合诊断标准,尽管他们同时和前瞻性地表现出明显的发病率。